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Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst

This study examined the preparation of isobornyl acetate/isoborneol from camphene using an α-hydroxyl carboxylic acid (HCA) composite catalyst. Through the study of the influencing factors, it was found that HCA and boric acid exhibited significant synergistic catalysis. Under optimal conditions, wh...

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Autores principales: Meng, Zhong-Lei, Qin, Rong-Xiu, Wen, Ru-Si, Li, Gui-Qing, Liang, Zhong-Yun, Xie, Jun-Kang, Zhou, Yong-Hong, Yang, Zhang-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964953/
https://www.ncbi.nlm.nih.gov/pubmed/36838861
http://dx.doi.org/10.3390/molecules28041875
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author Meng, Zhong-Lei
Qin, Rong-Xiu
Wen, Ru-Si
Li, Gui-Qing
Liang, Zhong-Yun
Xie, Jun-Kang
Zhou, Yong-Hong
Yang, Zhang-Qi
author_facet Meng, Zhong-Lei
Qin, Rong-Xiu
Wen, Ru-Si
Li, Gui-Qing
Liang, Zhong-Yun
Xie, Jun-Kang
Zhou, Yong-Hong
Yang, Zhang-Qi
author_sort Meng, Zhong-Lei
collection PubMed
description This study examined the preparation of isobornyl acetate/isoborneol from camphene using an α-hydroxyl carboxylic acid (HCA) composite catalyst. Through the study of the influencing factors, it was found that HCA and boric acid exhibited significant synergistic catalysis. Under optimal conditions, when tartaric acid–boric acid was used as the catalyst, the conversion of camphene and the gas chromatography (GC) content and selectivity of isobornyl acetate were 92.9%, 88.5%, and 95.3%, respectively. With the increase in the ratio of water to acetic acid, the GC content and selectivity of isobornol in the product increased, but the conversion of camphene decreased. The yield of isobornol was increased by adding ethyl acetate or titanium sulfate/zirconium sulfate to form a ternary composite catalyst. When a ternary complex of titanium sulfate, tartaric acid, and boric acid was used as the catalyst, the GC content of isobornol in the product reached 55.6%. Under solvent-free conditions, mandelic acid–boric acid could catalyze the hydration reaction of camphene, the GC content of isoborneol in the product reached 26.1%, and the selectivity of isoborneol was 55.9%. The HCA–boric acid composite catalyst can use aqueous acetic acid as a raw material, which is also beneficial for the reuse of the catalyst.
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spelling pubmed-99649532023-02-26 Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst Meng, Zhong-Lei Qin, Rong-Xiu Wen, Ru-Si Li, Gui-Qing Liang, Zhong-Yun Xie, Jun-Kang Zhou, Yong-Hong Yang, Zhang-Qi Molecules Article This study examined the preparation of isobornyl acetate/isoborneol from camphene using an α-hydroxyl carboxylic acid (HCA) composite catalyst. Through the study of the influencing factors, it was found that HCA and boric acid exhibited significant synergistic catalysis. Under optimal conditions, when tartaric acid–boric acid was used as the catalyst, the conversion of camphene and the gas chromatography (GC) content and selectivity of isobornyl acetate were 92.9%, 88.5%, and 95.3%, respectively. With the increase in the ratio of water to acetic acid, the GC content and selectivity of isobornol in the product increased, but the conversion of camphene decreased. The yield of isobornol was increased by adding ethyl acetate or titanium sulfate/zirconium sulfate to form a ternary composite catalyst. When a ternary complex of titanium sulfate, tartaric acid, and boric acid was used as the catalyst, the GC content of isobornol in the product reached 55.6%. Under solvent-free conditions, mandelic acid–boric acid could catalyze the hydration reaction of camphene, the GC content of isoborneol in the product reached 26.1%, and the selectivity of isoborneol was 55.9%. The HCA–boric acid composite catalyst can use aqueous acetic acid as a raw material, which is also beneficial for the reuse of the catalyst. MDPI 2023-02-16 /pmc/articles/PMC9964953/ /pubmed/36838861 http://dx.doi.org/10.3390/molecules28041875 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Meng, Zhong-Lei
Qin, Rong-Xiu
Wen, Ru-Si
Li, Gui-Qing
Liang, Zhong-Yun
Xie, Jun-Kang
Zhou, Yong-Hong
Yang, Zhang-Qi
Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst
title Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst
title_full Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst
title_fullStr Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst
title_full_unstemmed Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst
title_short Study on Synthesizing Isobornyl Acetate/Isoborneol from Camphene Using α-Hydroxyl Carboxylic Acid Composite Catalyst
title_sort study on synthesizing isobornyl acetate/isoborneol from camphene using α-hydroxyl carboxylic acid composite catalyst
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964953/
https://www.ncbi.nlm.nih.gov/pubmed/36838861
http://dx.doi.org/10.3390/molecules28041875
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