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An Approach to Evaluate the Effective Cytoplasmic Concentration of Bioactive Agents Interacting with a Selected Intracellular Target Protein

To compare the effectiveness of various bioactive agents reversibly acting within a cell on a target intracellular macromolecule, it is necessary to assess effective cytoplasmic concentrations of the delivered bioactive agents. In this work, based on a simple equilibrium model and the cellular therm...

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Detalles Bibliográficos
Autores principales:	Khramtsov, Yuri V., Ulasov, Alexey V., Rosenkranz, Andrey A., Slastnikova, Tatiana A., Lupanova, Tatiana N., Georgiev, Georgii P., Sobolev, Alexander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965106/ https://www.ncbi.nlm.nih.gov/pubmed/36839653 http://dx.doi.org/10.3390/pharmaceutics15020324

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