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Cyclosporine A-Loaded Ternary Solid Dispersion Prepared with Fine Droplet Drying Process for Improvement of Storage Stability and Oral Bioavailability

This study aimed to develop a cyclosporine A (CsA)-loaded ternary solid dispersion (tSD/CsA) to improve the storage stability of a solid dispersion (SD) system and the oral absorbability of CsA. Hydroxypropyl cellulose (HPC) and hydroxypropyl methylcellulose acetate succinate (HPMCAS) were selected...

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Detalles Bibliográficos
Autores principales: Moritani, Tatsuru, Usui, Hayato, Morinaga, Tadahiko, Sato, Hideyuki, Onoue, Satomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965122/
https://www.ncbi.nlm.nih.gov/pubmed/36839893
http://dx.doi.org/10.3390/pharmaceutics15020571

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