Airborne Exposure of the Cornea to PM(10) Induces Oxidative Stress and Disrupts Nrf2 Mediated Anti-Oxidant Defenses

The purpose of this study is to test the effects of whole-body animal exposure to airborne particulate matter (PM) with an aerodynamic diameter of <10 μm (PM(10)) in the mouse cornea and in vitro. C57BL/6 mice were exposed to control or 500 µg/m(3) PM(10) for 2 weeks. In vivo, reduced glutathione...

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Detalles Bibliográficos
Autores principales: Somayajulu, Mallika, McClellan, Sharon A., Wright, Robert, Pitchaikannu, Ahalya, Croniger, Bridget, Zhang, Kezhong, Hazlett, Linda D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965133/
https://www.ncbi.nlm.nih.gov/pubmed/36835320
http://dx.doi.org/10.3390/ijms24043911

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