Injectable Polypeptide Hydrogel Depots Containing Dual Immune Checkpoint Inhibitors and Doxorubicin for Improved Tumor Immunotherapy and Post-Surgical Tumor Treatment

In this work, we developed a strategy for local chemo-immunotherapy through simultaneous incorporation of dual immune checkpoint blockade (ICB) antibodies, anti-cytotoxic T-lymphocyte-associated protein 4 (aCTLA-4) and anti-programmed cell death protein 1 (aPD-1), and a chemotherapy drug, doxorubici...

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Detalles Bibliográficos
Autores principales: Chen, Zhixiong, Rong, Yan, Ding, Junfeng, Cheng, Xueliang, Chen, Xuesi, He, Chaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965187/
https://www.ncbi.nlm.nih.gov/pubmed/36839750
http://dx.doi.org/10.3390/pharmaceutics15020428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965187/
https://www.ncbi.nlm.nih.gov/pubmed/36839750
http://dx.doi.org/10.3390/pharmaceutics15020428

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