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Binding of Different Cyclosporin Variants to Micelles Evidenced by NMR and MD Simulations

Peptides play a critical role in the life of organisms, performing completely different functions. The biological activity of some peptides, such as cyclosporins, can be determined by the degree of membrane permeability. Thus, it becomes important to study how the molecule interacts with lipid bilay...

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Detalles Bibliográficos
Autores principales: Kobchikova, Polina P., Efimov, Sergey V., Klochkov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965255/
https://www.ncbi.nlm.nih.gov/pubmed/36837699
http://dx.doi.org/10.3390/membranes13020196