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Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells
Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965396/ https://www.ncbi.nlm.nih.gov/pubmed/36826902 http://dx.doi.org/10.3390/jfb14020103 |
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author | da Silva, Zuleni Alexandre Melo, Wallacy Watson Pereira Ferreira, Hadassa Helez Neves Lima, Rafael Rodrigues Souza-Rodrigues, Renata Duarte |
author_facet | da Silva, Zuleni Alexandre Melo, Wallacy Watson Pereira Ferreira, Hadassa Helez Neves Lima, Rafael Rodrigues Souza-Rodrigues, Renata Duarte |
author_sort | da Silva, Zuleni Alexandre |
collection | PubMed |
description | Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refractory patients. Tissue engineering has been presented as a promising therapy. Our study aimed to investigate trends and point out future research directions on TMD and stem cells. A comprehensive search was carried out in the Web of Science Core Collection (WoS-CC) in October 2022. The bibliometric parameters were analyzed through descriptive statistics and graphical mapping. Thus, 125 papers, published between 1992 and 2022 in 65 journals, were selected. The period with the highest number of publications and citations was between 2012 and 2022. China has produced the most publications on the subject. The most frequently used keywords were “cartilage”, “temporomandibular joint”, “mesenchymal stem cells”, and “osteoarthritis”. Moreover, the primary type of study was in vivo. It was noticed that using stem cells to improve temporomandibular joint repair and regeneration is a significant subject of investigation. Nonetheless, a greater understanding of the biological interaction and the benefits of using these cells in patients with TMD is required. |
format | Online Article Text |
id | pubmed-9965396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99653962023-02-26 Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells da Silva, Zuleni Alexandre Melo, Wallacy Watson Pereira Ferreira, Hadassa Helez Neves Lima, Rafael Rodrigues Souza-Rodrigues, Renata Duarte J Funct Biomater Review Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refractory patients. Tissue engineering has been presented as a promising therapy. Our study aimed to investigate trends and point out future research directions on TMD and stem cells. A comprehensive search was carried out in the Web of Science Core Collection (WoS-CC) in October 2022. The bibliometric parameters were analyzed through descriptive statistics and graphical mapping. Thus, 125 papers, published between 1992 and 2022 in 65 journals, were selected. The period with the highest number of publications and citations was between 2012 and 2022. China has produced the most publications on the subject. The most frequently used keywords were “cartilage”, “temporomandibular joint”, “mesenchymal stem cells”, and “osteoarthritis”. Moreover, the primary type of study was in vivo. It was noticed that using stem cells to improve temporomandibular joint repair and regeneration is a significant subject of investigation. Nonetheless, a greater understanding of the biological interaction and the benefits of using these cells in patients with TMD is required. MDPI 2023-02-13 /pmc/articles/PMC9965396/ /pubmed/36826902 http://dx.doi.org/10.3390/jfb14020103 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review da Silva, Zuleni Alexandre Melo, Wallacy Watson Pereira Ferreira, Hadassa Helez Neves Lima, Rafael Rodrigues Souza-Rodrigues, Renata Duarte Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells |
title | Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells |
title_full | Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells |
title_fullStr | Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells |
title_full_unstemmed | Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells |
title_short | Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells |
title_sort | global trends and future research directions for temporomandibular disorders and stem cells |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965396/ https://www.ncbi.nlm.nih.gov/pubmed/36826902 http://dx.doi.org/10.3390/jfb14020103 |
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