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Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells

Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refr...

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Detalles Bibliográficos
Autores principales: da Silva, Zuleni Alexandre, Melo, Wallacy Watson Pereira, Ferreira, Hadassa Helez Neves, Lima, Rafael Rodrigues, Souza-Rodrigues, Renata Duarte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965396/
https://www.ncbi.nlm.nih.gov/pubmed/36826902
http://dx.doi.org/10.3390/jfb14020103
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author da Silva, Zuleni Alexandre
Melo, Wallacy Watson Pereira
Ferreira, Hadassa Helez Neves
Lima, Rafael Rodrigues
Souza-Rodrigues, Renata Duarte
author_facet da Silva, Zuleni Alexandre
Melo, Wallacy Watson Pereira
Ferreira, Hadassa Helez Neves
Lima, Rafael Rodrigues
Souza-Rodrigues, Renata Duarte
author_sort da Silva, Zuleni Alexandre
collection PubMed
description Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refractory patients. Tissue engineering has been presented as a promising therapy. Our study aimed to investigate trends and point out future research directions on TMD and stem cells. A comprehensive search was carried out in the Web of Science Core Collection (WoS-CC) in October 2022. The bibliometric parameters were analyzed through descriptive statistics and graphical mapping. Thus, 125 papers, published between 1992 and 2022 in 65 journals, were selected. The period with the highest number of publications and citations was between 2012 and 2022. China has produced the most publications on the subject. The most frequently used keywords were “cartilage”, “temporomandibular joint”, “mesenchymal stem cells”, and “osteoarthritis”. Moreover, the primary type of study was in vivo. It was noticed that using stem cells to improve temporomandibular joint repair and regeneration is a significant subject of investigation. Nonetheless, a greater understanding of the biological interaction and the benefits of using these cells in patients with TMD is required.
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spelling pubmed-99653962023-02-26 Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells da Silva, Zuleni Alexandre Melo, Wallacy Watson Pereira Ferreira, Hadassa Helez Neves Lima, Rafael Rodrigues Souza-Rodrigues, Renata Duarte J Funct Biomater Review Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refractory patients. Tissue engineering has been presented as a promising therapy. Our study aimed to investigate trends and point out future research directions on TMD and stem cells. A comprehensive search was carried out in the Web of Science Core Collection (WoS-CC) in October 2022. The bibliometric parameters were analyzed through descriptive statistics and graphical mapping. Thus, 125 papers, published between 1992 and 2022 in 65 journals, were selected. The period with the highest number of publications and citations was between 2012 and 2022. China has produced the most publications on the subject. The most frequently used keywords were “cartilage”, “temporomandibular joint”, “mesenchymal stem cells”, and “osteoarthritis”. Moreover, the primary type of study was in vivo. It was noticed that using stem cells to improve temporomandibular joint repair and regeneration is a significant subject of investigation. Nonetheless, a greater understanding of the biological interaction and the benefits of using these cells in patients with TMD is required. MDPI 2023-02-13 /pmc/articles/PMC9965396/ /pubmed/36826902 http://dx.doi.org/10.3390/jfb14020103 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
da Silva, Zuleni Alexandre
Melo, Wallacy Watson Pereira
Ferreira, Hadassa Helez Neves
Lima, Rafael Rodrigues
Souza-Rodrigues, Renata Duarte
Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells
title Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells
title_full Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells
title_fullStr Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells
title_full_unstemmed Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells
title_short Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells
title_sort global trends and future research directions for temporomandibular disorders and stem cells
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965396/
https://www.ncbi.nlm.nih.gov/pubmed/36826902
http://dx.doi.org/10.3390/jfb14020103
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