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Exosome-Based Delivery of Super-Repressor IκBα Alleviates Alcohol-Associated Liver Injury in Mice

Activation of Kupffer cells (KCs) by gut-derived lipopolysaccharide (LPS) instigates nuclear factor-κB (NF-κB)-mediated inflammatory responses in alcohol-associated liver diseases (ALD). Here, we utilized a novel optogenetically engineered exosome technology called ‘exosomes for protein loading via...

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Detalles Bibliográficos
Autores principales:	Kim, Hee-Hoon, Shim, Young-Ri, Choi, Sung Eun, Falana, Tolulope Esther, Yoo, Jae-Kwang, Ahn, So-Hee, Park, Minhye, Seo, Hyangmi, Choi, Chulhee, Jeong, Won-Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965399/ https://www.ncbi.nlm.nih.gov/pubmed/36839957 http://dx.doi.org/10.3390/pharmaceutics15020636

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