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Characterization of Continuous Transcriptional Heterogeneity in High-Risk Blastemal-Type Wilms’ Tumors Using Unsupervised Machine Learning
Wilms’ tumors are pediatric malignancies that are thought to arise from faulty kidney development. They contain a wide range of poorly differentiated cell states resembling various distorted developmental stages of the fetal kidney, and as a result, differ between patients in a continuous manner tha...
Autores principales: | Trink, Yaron, Urbach, Achia, Dekel, Benjamin, Hohenstein, Peter, Goldberger, Jacob, Kalisky, Tomer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965420/ https://www.ncbi.nlm.nih.gov/pubmed/36834944 http://dx.doi.org/10.3390/ijms24043532 |
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