Cargando…

Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

Cancer is one of the major healthcare challenges across the globe. Several anticancer drugs are available on the market but they either lack specificity or have poor safety, severe side effects, and suffer from resistance. So, there is a dire need to develop safer and target-specific anticancer drug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Adarsh, Singh, Ankit Kumar, Singh, Harshwardhan, Vijayan, Veena, Kumar, Deepak, Naik, Jashwanth, Thareja, Suresh, Yadav, Jagat Pal, Pathak, Prateek, Grishina, Maria, Verma, Amita, Khalilullah, Habibullah, Jaremko, Mariusz, Emwas, Abdul-Hamid, Kumar, Pradeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965678/ https://www.ncbi.nlm.nih.gov/pubmed/37259442 http://dx.doi.org/10.3390/ph16020299

Ejemplares similares

Concept of Hybrid Drugs and Recent Advancements in Anticancer Hybrids
por: Singh, Ankit Kumar, et al.
Publicado: (2022)

Gaussian field-based 3D-QSAR and molecular simulation studies to design potent pyrimidine–sulfonamide hybrids as selective BRAF(V600E) inhibitors
por: Singh, Ankit Kumar, et al.
Publicado: (2022)

Challenges and Opportunities in the Crusade of BRAF Inhibitors: From 2002 to 2022
por: Singh, Ankit Kumar, et al.
Publicado: (2023)

Medicinal chemistry perspective of pyrido[2,3-d]pyrimidines as anticancer agents
por: Kumar, Adarsh, et al.
Publicado: (2023)

Guava Leaf Essential Oil as a Potent Antioxidant and Anticancer Agent: Validated through Experimental and Computational Study
por: Mandal, Ashok Kumar, et al.
Publicado: (2022)

Debelalactone Prevents Hepatic Cancer via Diminishing the Inflammatory Response and Oxidative Stress on Male Wistar Rats
por: Pathak, Prateek, et al.
Publicado: (2022)

In Silico Studies of Indole Derivatives as Antibacterial Agents
por: Shah, Mridul, et al.
Publicado: (2023)

Heterocyclic chemistry /
por: Gilchrist, T. L. (Thomas Lonsdale)
Publicado: (1997)

Heterocyclic chemistry
por: Joule, John Arthur
Publicado: (1995)

Heterocyclic chemistry /
por: Joule, J. A. (John Arthur)
Publicado: (2010)

Three Rings Schiff Base Ester Liquid Crystals: Experimental and Computational Approaches of Mesogenic Core Orientation Effect, Heterocycle Impact
por: Nada, Shady, et al.
Publicado: (2022)

Heterocycles in Medicinal Chemistry
por: Jampilek, Josef
Publicado: (2019)

The chemistry of heterocycles : structure, reactions, syntheses, and applications /
por: Eicher, Theophil, 1932-
Publicado: (2003)

The chemistry of heterocycles : structure, reactions, synthesis and applications
por: Eicher, Theophil, 1932-
Publicado: (1995)

Compound-Specific 1D (1)H NMR Pulse Sequence Selection for Metabolomics Analyses
por: Singh, Upendra, et al.
Publicado: (2023)

Classification of Clinical Isolates of Klebsiella pneumoniae Based on Their in vitro Biofilm Forming Capabilities and Elucidation of the Biofilm Matrix Chemistry With Special Reference to the Protein Content
por: Singh, Ashish Kumar, et al.
Publicado: (2019)

The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles
por: D’yachenko, Elisaveta V., et al.
Publicado: (2005)

Structural and Conformational Aspects in the Chemistry of Heterocycles
por: Shainyan, Bagrat A.
Publicado: (2020)

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics
por: Balasubramaniam, Bhuvaneshwari, et al.
Publicado: (2020)

Special Issue: Selected Papers from the Second Eurasian Meeting on Heterocyclic Chemistry: Heterocycles in Organic and Combinatorial Chemistry
por: Babaev, Eugene V., et al.
Publicado: (2003)

The biomechanics of Kansal Separator: A ‘2 in 1’ self-secured orthodontic spring separator
por: Kumar, Arun, et al.
Publicado: (2014)

Overview of Chemistry and Therapeutic Potential of Non-Nitrogen Heterocyclics as Anticonvulsant Agents
por: Pal, Rohit, et al.
Publicado: (2022)

Single crystal, Hirshfeld surface and theoretical analysis of methyl 4-hydroxybenzoate, a common cosmetic, drug and food preservative—Experiment versus theory
por: Sharfalddin, Abeer, et al.
Publicado: (2020)

In vitro and in silico evaluations of actinomycin X(2)and actinomycin D as potent anti-tuberculosis agents
por: Qureshi, Kamal Ahmad, et al.
Publicado: (2023)

Low-latency and High-Reliability FBMC Modulation scheme using Optimized Filter design for enabling NextG Real-time Smart Healthcare Applications
por: Adarsh, Abhinav, et al.
Publicado: (2022)

The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis
por: Erian, Ayman W., et al.
Publicado: (2003)

Molecular dynamics analysis of phytochemicals from Ageratina adenophora against COVID-19 main protease (M(pro)) and human angiotensin-converting enzyme 2 (ACE2)
por: Neupane, Netra Prasad, et al.
Publicado: (2021)

A β–Sitosterol Encapsulated Biocompatible Alginate/Chitosan Polymer Nanocomposite for the Treatment of Breast Cancer
por: Afzal, Obaid, et al.
Publicado: (2022)

Synthesis, biological evaluation and in-silico ADME studies of novel series of thiazolidin-2,4-dione derivatives as antimicrobial, antioxidant and anticancer agents
por: Kumar, Harsh, et al.
Publicado: (2022)

Epidemiological Characteristics of Patients Attending for Rabies Post-Exposure Prophylaxis at the Infectious Diseases Hospital of Lucknow, India
por: Sahu, Krishna Kumar, et al.
Publicado: (2015)

Aggregation of biologically important peptides and proteins: inhibition or acceleration depending on protein and metal ion concentrations
por: Poulson, Benjamin Gabriel, et al.
Publicado: (2019)

Therapeutic potential of heterocyclic pyrimidine scaffolds
por: Kumar, Sanjiv, et al.
Publicado: (2018)

Synthetic Methods, Chemistry, and the Anticonvulsant Activity of Thiadiazoles
por: Sharma, Bhawna, et al.
Publicado: (2013)

Deciphering the role of endophytic microbiome in postharvest diseases management of fruits: Opportunity areas in commercial up-scale production
por: Kumari, Madhuree, et al.
Publicado: (2022)

Complexation of uranyl (UO(2))(2+) with bidentate ligands: XRD, spectroscopic, computational, and biological studies
por: Sharfalddin, Abeer A., et al.
Publicado: (2021)

Practical and Computational Studies of Bivalence Metal Complexes of Sulfaclozine and Biological Studies
por: Sharfalddin, Abeer A, et al.
Publicado: (2021)

Untargeted metabolomics-based response analysis of temperature and insecticide exposure in Aedes aegypti
por: Singh, Poonam, et al.
Publicado: (2022)

Functional Outcome of Hemiarthroplasty of the Hip for Unstable Intertrochanteric Fractures of the Femur in Elderly Patients: A Prospective Study
por: Singh, Jasveer, et al.
Publicado: (2022)

Recent synthetic strategies for the construction of functionalized carbazoles and their heterocyclic motifs enabled by Lewis acids
por: Kumar, Marappan Pradeep, et al.
Publicado: (2023)

Nanocatalysts: applications for the synthesis of N-containing five-membered heterocycles
por: Jangir, Nidhi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2eirf60g6212vsddhfdprf9fpe