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The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan
Since the first discovery of severe fever with thrombocytopenia syndrome virus (SFTSV) in China in 2009, SFTSV has rapidly spread through other Asian countries, including Japan, Korea, Vietnam and Pakistan, in chronological order. Taiwan reported its first discovery of SFTSV in sheep and humans in 2...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965706/ https://www.ncbi.nlm.nih.gov/pubmed/36851653 http://dx.doi.org/10.3390/v15020441 |
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author | Kuan, Chih-Ying Lin, Tsai-Lu Ou, Shan-Chia Chuang, Shih-Te Chan, Jacky Peng-Wen Maeda, Ken Mizutani, Tetsuya Wu, Ming-Pin Lee, Fan Chan, Fang-Tse Chang, Chao-Chin Liang, Rui-Ling Yang, Sue-Fung Liu, Tsung-Ching Tu, Wu-Chun Tzeng, Hau-You Lee, Chia-Jung Lin, Chuen-Fu Lee, Hsu-Hsun Wu, Jhih-Hua Lo, Hsiao-Chien Tseng, Kuan-Chieh Hsu, Wei-Li Chou, Chi-Chung |
author_facet | Kuan, Chih-Ying Lin, Tsai-Lu Ou, Shan-Chia Chuang, Shih-Te Chan, Jacky Peng-Wen Maeda, Ken Mizutani, Tetsuya Wu, Ming-Pin Lee, Fan Chan, Fang-Tse Chang, Chao-Chin Liang, Rui-Ling Yang, Sue-Fung Liu, Tsung-Ching Tu, Wu-Chun Tzeng, Hau-You Lee, Chia-Jung Lin, Chuen-Fu Lee, Hsu-Hsun Wu, Jhih-Hua Lo, Hsiao-Chien Tseng, Kuan-Chieh Hsu, Wei-Li Chou, Chi-Chung |
author_sort | Kuan, Chih-Ying |
collection | PubMed |
description | Since the first discovery of severe fever with thrombocytopenia syndrome virus (SFTSV) in China in 2009, SFTSV has rapidly spread through other Asian countries, including Japan, Korea, Vietnam and Pakistan, in chronological order. Taiwan reported its first discovery of SFTSV in sheep and humans in 2020. However, the prevalence of SFTSV in domestic and wildlife animals and the geographic distribution of the virus within the island remain unknown. A total of 1324 animal samples, including 803 domestic ruminants, 521 wildlife animals and 47 tick pools, were collected from March 2021 to December 2022 from 12 counties and one terrestrial island. The viral RNA was detected by a one-step real-time reverse transcription polymerase chain reaction (RT-PCR). Overall, 29.9% (240/803) of ruminants showed positive SFTSV RNA. Sheep had the highest viral RNA prevalence of 60% (30/50), followed by beef cattle at 28.4% (44/155), goats at 28.3% (47/166), and dairy cows at 27.5% (119/432). The bovine as a total of dairy cow and beef cattle was 27.8% (163/587). The viral RNA prevalence in ticks (predominantly Rhipicephalus microplus) was similar to those of ruminants at 27.7% (13/47), but wild animals exhibited a much lower prevalence at 1.3% (7/521). Geographically the distribution of positivity was quite even, being 33%, 29.1%, 27.5% and 37.5% for northern, central, southern and eastern Taiwan, respectively. Statistically, the positive rate of beef cattle in the central region (55.6%) and dairy cattle in the eastern region (40.6%) were significantly higher than the other regions; and the prevalence in Autumn (September–November) was significantly higher than in the other seasons (p < 0.001). The nationwide study herein revealed for the first time the wide distribution and high prevalence of SFTSV in both domestic animals and ticks in Taiwan. Considering the high mortality rate in humans, surveillance of other animal species, particularly those in close contact with humans, and instigation of protective measures for farmers, veterinarians, and especially older populations visiting or living near farms or rural areas should be prioritized. |
format | Online Article Text |
id | pubmed-9965706 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99657062023-02-26 The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan Kuan, Chih-Ying Lin, Tsai-Lu Ou, Shan-Chia Chuang, Shih-Te Chan, Jacky Peng-Wen Maeda, Ken Mizutani, Tetsuya Wu, Ming-Pin Lee, Fan Chan, Fang-Tse Chang, Chao-Chin Liang, Rui-Ling Yang, Sue-Fung Liu, Tsung-Ching Tu, Wu-Chun Tzeng, Hau-You Lee, Chia-Jung Lin, Chuen-Fu Lee, Hsu-Hsun Wu, Jhih-Hua Lo, Hsiao-Chien Tseng, Kuan-Chieh Hsu, Wei-Li Chou, Chi-Chung Viruses Article Since the first discovery of severe fever with thrombocytopenia syndrome virus (SFTSV) in China in 2009, SFTSV has rapidly spread through other Asian countries, including Japan, Korea, Vietnam and Pakistan, in chronological order. Taiwan reported its first discovery of SFTSV in sheep and humans in 2020. However, the prevalence of SFTSV in domestic and wildlife animals and the geographic distribution of the virus within the island remain unknown. A total of 1324 animal samples, including 803 domestic ruminants, 521 wildlife animals and 47 tick pools, were collected from March 2021 to December 2022 from 12 counties and one terrestrial island. The viral RNA was detected by a one-step real-time reverse transcription polymerase chain reaction (RT-PCR). Overall, 29.9% (240/803) of ruminants showed positive SFTSV RNA. Sheep had the highest viral RNA prevalence of 60% (30/50), followed by beef cattle at 28.4% (44/155), goats at 28.3% (47/166), and dairy cows at 27.5% (119/432). The bovine as a total of dairy cow and beef cattle was 27.8% (163/587). The viral RNA prevalence in ticks (predominantly Rhipicephalus microplus) was similar to those of ruminants at 27.7% (13/47), but wild animals exhibited a much lower prevalence at 1.3% (7/521). Geographically the distribution of positivity was quite even, being 33%, 29.1%, 27.5% and 37.5% for northern, central, southern and eastern Taiwan, respectively. Statistically, the positive rate of beef cattle in the central region (55.6%) and dairy cattle in the eastern region (40.6%) were significantly higher than the other regions; and the prevalence in Autumn (September–November) was significantly higher than in the other seasons (p < 0.001). The nationwide study herein revealed for the first time the wide distribution and high prevalence of SFTSV in both domestic animals and ticks in Taiwan. Considering the high mortality rate in humans, surveillance of other animal species, particularly those in close contact with humans, and instigation of protective measures for farmers, veterinarians, and especially older populations visiting or living near farms or rural areas should be prioritized. MDPI 2023-02-05 /pmc/articles/PMC9965706/ /pubmed/36851653 http://dx.doi.org/10.3390/v15020441 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kuan, Chih-Ying Lin, Tsai-Lu Ou, Shan-Chia Chuang, Shih-Te Chan, Jacky Peng-Wen Maeda, Ken Mizutani, Tetsuya Wu, Ming-Pin Lee, Fan Chan, Fang-Tse Chang, Chao-Chin Liang, Rui-Ling Yang, Sue-Fung Liu, Tsung-Ching Tu, Wu-Chun Tzeng, Hau-You Lee, Chia-Jung Lin, Chuen-Fu Lee, Hsu-Hsun Wu, Jhih-Hua Lo, Hsiao-Chien Tseng, Kuan-Chieh Hsu, Wei-Li Chou, Chi-Chung The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan |
title | The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan |
title_full | The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan |
title_fullStr | The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan |
title_full_unstemmed | The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan |
title_short | The First Nationwide Surveillance of Severe Fever with Thrombocytopenia Syndrome in Ruminants and Wildlife in Taiwan |
title_sort | first nationwide surveillance of severe fever with thrombocytopenia syndrome in ruminants and wildlife in taiwan |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965706/ https://www.ncbi.nlm.nih.gov/pubmed/36851653 http://dx.doi.org/10.3390/v15020441 |
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