Cargando…

Presence of Polyketide Synthase (PKS) Gene and Counterpart Virulence Determinants in Klebsiella pneumoniae Strains Enhances Colorectal Cancer Progression In-Vitro

Klebsiella pneumoniae (K. pneumoniae) colonizes the human gut and is a causative factor of pyogenic liver abscess (PLA). Retrospective studies conducted on K. pneumoniae PLA patients revealed subsequent CRC development in later years of their life with increasing prevalence of these strains harbouri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaur, Christina Parvinder, Iyadorai, Thevambiga, Sears, Cynthia, Roslani, April Camilla, Vadivelu, Jamuna, Samudi, Chandramathi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965769/ https://www.ncbi.nlm.nih.gov/pubmed/36838407 http://dx.doi.org/10.3390/microorganisms11020443

Ejemplares similares

Prevalence and association of pks(+) Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia
por: Iyadorai, Thevambiga, et al.
Publicado: (2020)

Polyketide synthases of Diaporthe helianthi and involvement of DhPKS1 in virulence on sunflower
por: Ruocco, Michelina, et al.
Publicado: (2018)

Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13
por: Kim, Sun Kyung, et al.
Publicado: (2023)

The Interpretation of the Role of a Polyketide Synthase ClPKS18 in the Pathogenicity of Curvularia lunata
por: Lu, Zhixiang, et al.
Publicado: (2022)

Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis
por: Bon, Cécile, et al.
Publicado: (2022)

Persistent infection due to a small-colony variant of Burkholderia pseudomallei leads to PD-1 upregulation on circulating immune cells and mononuclear infiltration in viscera of experimental BALB/c mice
por: See, Jia-Xiang, et al.
Publicado: (2017)

Metabolomic Analysis Demonstrates the Impacts of Polyketide Synthases PKS14 and PKS15 on the Production of Beauvericins, Bassianolide, Enniatin A, and Ferricrocin in Entomopathogen Beauveria bassiana
por: Toopaang, Wachiraporn, et al.
Publicado: (2023)

The polyketide synthase PKS15 has a crucial role in cell wall formation in Beauveria bassiana
por: Udompaisarn, Somsiri, et al.
Publicado: (2020)

Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase (pks) Island
por: Suresh, Arya, et al.
Publicado: (2021)

High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia
por: Drewes, Julia L., et al.
Publicado: (2017)

Author Correction: High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia
por: Drewes, Julia L., et al.
Publicado: (2019)

An Overview of the Medicinally Important Plant Type III PKS Derived Polyketides
por: Bisht, Renu, et al.
Publicado: (2021)

Metabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa
por: Loke, Mun Fai, et al.
Publicado: (2018)

Experimental Persistent Infection of BALB/c Mice with Small-Colony Variants of Burkholderia pseudomallei Leads to Concurrent Upregulation of PD-1 on T Cells and Skewed Th1 and Th17 Responses
por: See, Jia-Xiang, et al.
Publicado: (2016)

Involvement of a Polyketide Synthetase ClPKS18 in the Regulation of Vegetative Growth, Melanin and Toxin Synthesis, and Virulence in Curvularia lunata
por: Gao, Jin-Xin, et al.
Publicado: (2017)

Engineering Polyketide Synthases
por: Katz, Leonard
Publicado: (2002)

Experimental exposure of Burkholderia pseudomallei crude culture filtrate upregulates PD-1 on T lymphocytes
por: Menon, Nivedita, et al.
Publicado: (2020)

Prevalence of pks genotoxin among hospital-acquired Klebsiella pneumoniae
por: El-Ashry, Amira H., et al.
Publicado: (2022)

Genomic and clinical characterization of Klebsiella pneumoniae carrying the pks island
por: Wang, Zhiqian, et al.
Publicado: (2023)

The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases
por: Kwan, David H., et al.
Publicado: (2011)

Mycobacterium tuberculosis pks12 Produces a Novel Polyketide Presented by CD1c to T Cells
por: Matsunaga, Isamu, et al.
Publicado: (2004)

Characterization of NRPS and PKS genes involved in the biosynthesis of SMs in Alternaria dauci including the phytotoxic polyketide aldaulactone
por: Courtial, Julia, et al.
Publicado: (2022)

A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones
por: Meoded, Roy A., et al.
Publicado: (2018)

Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature
por: Paolo, William F, et al.
Publicado: (2006)

Genetic and Functional Analysis of the pks Gene in Clinical Klebsiella pneumoniae Isolates
por: Luo, Chenshuo, et al.
Publicado: (2023)

Biosynthesis of aromatic polyketides in microorganisms using type II polyketide synthases
por: Wang, Jia, et al.
Publicado: (2020)

Engineered biosynthesis of plant polyketides by type III polyketide synthases in microorganisms
por: Liu, Chang, et al.
Publicado: (2022)

Module-Based Polyketide Synthase Engineering for de Novo Polyketide Biosynthesis
por: Nava, Alberto A., et al.
Publicado: (2023)

Activation of a Silent Polyketide Synthase SlPKS4 Encoding the C(7)-Methylated Isocoumarin in a Marine-Derived Fungus Simplicillium lamellicola HDN13-430
por: Yu, Jing, et al.
Publicado: (2023)

Prevalence of pks gene cluster and characteristics of Klebsiella pneumoniae‐induced bloodstream infections
por: Lan, You, et al.
Publicado: (2019)

Traffic Control in Modular Polyketide Synthases
por: Finzel, Kara, et al.
Publicado: (2016)

Structure of a modular polyketide synthase
por: Dutta, Somnath, et al.
Publicado: (2014)

Acyltransferases as Tools for Polyketide Synthase Engineering
por: Musiol-Kroll, Ewa Maria, et al.
Publicado: (2018)

Engineered Biosynthesis of Regioselectively Modified Aromatic Polyketides Using Bimodular Polyketide Synthases
por: Tang, Yi, et al.
Publicado: (2004)

Novel Type III Polyketide Synthases Biosynthesize Methylated Polyketides in Mycobacterium marinum
por: Parvez, Amreesh, et al.
Publicado: (2018)

Corrigendum: Engineered biosynthesis of plant polyketides by type III polyketide synthases in microorganisms
por: Liu, Chang, et al.
Publicado: (2022)

Interaction between Polyketide Synthase and Transporter Suggests Coupled Synthesis and Export of Virulence Lipid in M. tuberculosis
por: Jain, Madhulika, et al.
Publicado: (2005)

A polyketide synthase from Verticillium dahliae modulates melanin biosynthesis and hyphal growth to promote virulence
por: Li, Huan, et al.
Publicado: (2022)

ASMPKS: an analysis system for modular polyketide synthases
por: Tae, Hongseok, et al.
Publicado: (2007)

The Origins of Specificity in Polyketide Synthase Protein Interactions
por: Thattai, Mukund, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_td4f3ej8l8940ohaiie1pvijf7