Development of an In Vitro Test Method to Replace an Animal-Based Potency Test for Pertactin Antigen in Multivalent Vaccines

There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present ethical concerns. The development of relevant in vitro assays is part of the solution. Using pertactin (PRN) antigen as an example in DTaP-IPV...

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Detalles Bibliográficos
Autores principales: Szeto, Jason, Beharry, Aruun, Chen, Tricia, Zholumbetov, Eric, Daigneault, Emilie, Ming, Marin, Lounsbury, Iain, Eng, Nelson, Thangavadivel, Nemika, Jin, Robbie, Denis-Jacquot, Aurélie, Azad, Bahram Behnam, Li, Meili, Keizner, Diana, Liu, Marcus, Lee, Sophia S. F., He, Kai, Gajewska, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965796/
https://www.ncbi.nlm.nih.gov/pubmed/36851153
http://dx.doi.org/10.3390/vaccines11020275

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