Ex Vivo Blockade of the PD-1 Pathway Improves Recall IFNγ Responses of HIV-Infected Persons on Antiretroviral Therapy

Despite antiretroviral therapy (ART), immune exhaustion persists in HIV infection and limits T cell responses to HIV or other pathogens. Moreover, HIV infection results in the loss of pre-existing immunity. Here, we investigated the effect of blocking the PD-1 pathway on recall IFNγ responses to tet...

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Detalles Bibliográficos
Autores principales: Fischhaber, Natalie, Schmiedeberg, Moritz, Kübel, Sabrina, Harrer, Ellen G., Harrer, Thomas, Nganou-Makamdop, Krystelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965969/
https://www.ncbi.nlm.nih.gov/pubmed/36851089
http://dx.doi.org/10.3390/vaccines11020211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965969/
https://www.ncbi.nlm.nih.gov/pubmed/36851089
http://dx.doi.org/10.3390/vaccines11020211

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