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CREB Is Activated by the SCF/KIT Axis in a Partially ERK-Dependent Manner and Orchestrates Survival and the Induction of Immediate Early Genes in Human Skin Mast Cells

cAMP response element binding protein (CREB) functions as a prototypical stimulus-inducible transcription factor (TF) that initiates multiple cellular changes in response to activation. Despite pronounced expression in mast cells (MCs), CREB function is surprisingly ill-defined in the lineage. Skin...

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Detalles Bibliográficos
Autores principales: Franke, Kristin, Bal, Gürkan, Li, Zhuoran, Zuberbier, Torsten, Babina, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966046/
https://www.ncbi.nlm.nih.gov/pubmed/36835547
http://dx.doi.org/10.3390/ijms24044135