Pediatric Systemic Lupus Erythematous in COVID-19 Era

Pediatric systemic lupus erythematosus is a chronic autoimmune disorder with a highly variable course and prognosis. It results in functional abnormalities in the immune system due to intrinsic factors and the use of immunosuppressive therapies associated with underlying comorbidities seem to increa...

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Autores principales: Lupu, Ancuta, Miron, Ingrith Crenguta, Gavrilovici, Cristina, Raileanu, Anca Adam, Starcea, Iuliana Magdalena, Ioniuc, Ileana, Azoicai, Alice, Mocanu, Adriana, Butnariu, Lacramioara Ionela, Dragan, Felicia, Lupu, Vasile Valeriu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966057/
https://www.ncbi.nlm.nih.gov/pubmed/36851487
http://dx.doi.org/10.3390/v15020272
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author Lupu, Ancuta
Miron, Ingrith Crenguta
Gavrilovici, Cristina
Raileanu, Anca Adam
Starcea, Iuliana Magdalena
Ioniuc, Ileana
Azoicai, Alice
Mocanu, Adriana
Butnariu, Lacramioara Ionela
Dragan, Felicia
Lupu, Vasile Valeriu
author_facet Lupu, Ancuta
Miron, Ingrith Crenguta
Gavrilovici, Cristina
Raileanu, Anca Adam
Starcea, Iuliana Magdalena
Ioniuc, Ileana
Azoicai, Alice
Mocanu, Adriana
Butnariu, Lacramioara Ionela
Dragan, Felicia
Lupu, Vasile Valeriu
author_sort Lupu, Ancuta
collection PubMed
description Pediatric systemic lupus erythematosus is a chronic autoimmune disorder with a highly variable course and prognosis. It results in functional abnormalities in the immune system due to intrinsic factors and the use of immunosuppressive therapies associated with underlying comorbidities seem to increase the risk of severe COVID-19 and poor outcomes of the disease in pediatric systemic lupus erythematosus (SLE) patients. The aim of this review is to obtain a better understanding of the existing link between this new viral infection and pediatric lupus. We have analyzed the characteristics of newly diagnosed cases of pediatric SLE following COVID-19 which have been reported in the literature and which describe the impact that COVID-19 has on patients already suffering with pediatric SLE.
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spelling pubmed-99660572023-02-26 Pediatric Systemic Lupus Erythematous in COVID-19 Era Lupu, Ancuta Miron, Ingrith Crenguta Gavrilovici, Cristina Raileanu, Anca Adam Starcea, Iuliana Magdalena Ioniuc, Ileana Azoicai, Alice Mocanu, Adriana Butnariu, Lacramioara Ionela Dragan, Felicia Lupu, Vasile Valeriu Viruses Review Pediatric systemic lupus erythematosus is a chronic autoimmune disorder with a highly variable course and prognosis. It results in functional abnormalities in the immune system due to intrinsic factors and the use of immunosuppressive therapies associated with underlying comorbidities seem to increase the risk of severe COVID-19 and poor outcomes of the disease in pediatric systemic lupus erythematosus (SLE) patients. The aim of this review is to obtain a better understanding of the existing link between this new viral infection and pediatric lupus. We have analyzed the characteristics of newly diagnosed cases of pediatric SLE following COVID-19 which have been reported in the literature and which describe the impact that COVID-19 has on patients already suffering with pediatric SLE. MDPI 2023-01-18 /pmc/articles/PMC9966057/ /pubmed/36851487 http://dx.doi.org/10.3390/v15020272 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lupu, Ancuta
Miron, Ingrith Crenguta
Gavrilovici, Cristina
Raileanu, Anca Adam
Starcea, Iuliana Magdalena
Ioniuc, Ileana
Azoicai, Alice
Mocanu, Adriana
Butnariu, Lacramioara Ionela
Dragan, Felicia
Lupu, Vasile Valeriu
Pediatric Systemic Lupus Erythematous in COVID-19 Era
title Pediatric Systemic Lupus Erythematous in COVID-19 Era
title_full Pediatric Systemic Lupus Erythematous in COVID-19 Era
title_fullStr Pediatric Systemic Lupus Erythematous in COVID-19 Era
title_full_unstemmed Pediatric Systemic Lupus Erythematous in COVID-19 Era
title_short Pediatric Systemic Lupus Erythematous in COVID-19 Era
title_sort pediatric systemic lupus erythematous in covid-19 era
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966057/
https://www.ncbi.nlm.nih.gov/pubmed/36851487
http://dx.doi.org/10.3390/v15020272
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