Cargando…

Endogenous miRNA-Based Innate-Immunity against SARS-CoV-2 Invasion of the Brain

The severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19, possesses an unusually large positive-sense, single-stranded viral RNA (ssvRNA) genome of about ~29,903 nucleotides (nt). In many respects, this ssvRNA resembles a very large, polycistronic messenger R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lukiw, Walter J., Pogue, Aileen I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966119/ https://www.ncbi.nlm.nih.gov/pubmed/36834773 http://dx.doi.org/10.3390/ijms24043363

Ejemplares similares

SARS-CoV-2 Infectivity and Neurological Targets in the Brain
por: Lukiw, Walter J., et al.
Publicado: (2020)

SARS-CoV-2 Invasion and Pathological Links to Prion Disease
por: Lukiw, Walter J., et al.
Publicado: (2022)

MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer’s Disease (AD)-Novel and Unique Pathological Features
por: Zhao, Yuhai, et al.
Publicado: (2015)

microRNA, the Innate-Immune System and SARS-CoV-2
por: Hill, James M., et al.
Publicado: (2022)

Evolution of microRNA (miRNA) Structure and Function in Plants and Animals: Relevance to Aging and Disease
por: Pogue, Aileen I, et al.
Publicado: (2014)

microRNA Heterogeneity, Innate-Immune Defense and the Efficacy of SARS-CoV-2 Infection—A Commentary
por: Lukiw, Walter J.
Publicado: (2021)

Downregulation of Neurofilament Light Chain Expression in Human Neuronal-Glial Cell Co-Cultures by a Microbiome-Derived Lipopolysaccharide-Induced miRNA-30b-5p
por: Pogue, Aileen I., et al.
Publicado: (2022)

Deficits in the miRNA-34a-regulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer's disease (AD); an update
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2014)

Pathogenic microRNAs Common to Brain and Retinal Degeneration; Recent Observations in Alzheimer’s Disease and Age-Related Macular Degeneration
por: Hill, James M., et al.
Publicado: (2015)

The Mobilization of Aluminum into the Biosphere
por: Pogue, Aileen I., et al.
Publicado: (2014)

Natural and Synthetic Neurotoxins in Our Environment: From Alzheimer’s Disease (AD) to Autism Spectrum Disorder (ASD)
por: Pogue, Aileen I, et al.
Publicado: (2016)

Vesicular Transport of Encapsulated microRNA between Glial and Neuronal Cells
por: Lukiw, Walter J., et al.
Publicado: (2020)

microRNA-146a-5p, Neurotropic Viral Infection and Prion Disease (PrD)
por: Pogue, Aileen I., et al.
Publicado: (2021)

MicroRNA (miRNA) Complexity in Alzheimer’s Disease (AD)
por: Lukiw, Walter J.
Publicado: (2023)

NF-κB-regulated, proinflammatory miRNAs in Alzheimer's disease
por: Lukiw, Walter J
Publicado: (2012)

Fission Impossible: Stabilized miRNA-Based Analogs in Neurodegenerative Disease
por: Lukiw, Walter J.
Publicado: (2022)

Innate immune recognition against SARS-CoV-2
por: Yamada, Taisho, et al.
Publicado: (2023)

Antagonism of NF-κB-up-regulated micro RNAs (miRNAs) in sporadic Alzheimer's disease (AD)—anti-NF-κB vs. anti-miRNA strategies
por: Lukiw, Walter J.
Publicado: (2013)

Generation of Reactive Oxygen Species (ROS) and Pro-Inflammatory Signaling in Human Brain Cells in Primary Culture
por: Lukiw, Walter J., et al.
Publicado: (2012)

Effect of SARS-CoV-2 infection on host competing endogenous RNA and miRNA network
por: Ari Yuka, Selcen, et al.
Publicado: (2021)

TREM2 signaling, miRNA-34a and the extinction of phagocytosis
por: Zhao, Yuhai, et al.
Publicado: (2013)

Synergism in aluminum and mercury neurotoxicity
por: Alexandrov, Peter N, et al.
Publicado: (2018)

Signature miRNAs Involved in the Innate Immunity of Invertebrates
por: Yang, Geng, et al.
Publicado: (2012)

Increase in NF-κB-sensitive miRNA-146a and miRNA-155 in multiple sclerosis (MS) and pro-inflammatory neurodegeneration
por: Devier, Deidre J., et al.
Publicado: (2015)

Devil's tools: SARS-CoV-2 antagonists against innate immunity
por: Xu, Duo, et al.
Publicado: (2021)

TLRs: Innate Immune Sentries against SARS-CoV-2 Infection
por: Mantovani, Stefania, et al.
Publicado: (2023)

Comparing miRNAs and viroids; highly conserved molecular mechanisms for the transmission of genetic information
por: Hill, James M., et al.
Publicado: (2014)

MiRNAs and lncRNAs in the regulation of innate immune signaling
por: Gareev, Ilgiz, et al.
Publicado: (2023)

Viral miRNAs Alter Host Cell miRNA Profiles and Modulate Innate Immune Responses
por: Naqvi, Afsar R., et al.
Publicado: (2018)

Brain innate immune response via miRNA-TLR7 sensing in polymicrobial sepsis
por: Zou, Lin, et al.
Publicado: (2022)

SARS-CoV-2 Neuroinvasion, Inflammatory Neurodegeneration and Alzheimer's Disease
por: Zhao, Yuhai, et al.
Publicado: (2022)

The Gastrointestinal Tract Microbiome and Potential Link to Alzheimer’s Disease
por: Hill, James M., et al.
Publicado: (2014)

Systemic Inflammation in C57BL/6J Mice Receiving Dietary Aluminum Sulfate; Up-Regulation of the Pro-Inflammatory Cytokines IL-6 and TNFα, C-Reactive Protein (CRP) and miRNA-146a in Blood Serum
por: Pogue, AI, et al.
Publicado: (2017)

Variability in micro RNA (miRNA) abundance, speciation and complexity amongst different human populations and potential relevance to Alzheimer's disease (AD)
por: Lukiw, Walter J.
Publicado: (2013)

miRNAs and viroids utilize common strategies in genetic signal transfer
por: Hill, James M., et al.
Publicado: (2014)

SARS-CoV-2, the Angiotensin Converting Enzyme 2 (ACE2) Receptor and Alzheimer’s disease
por: Lukiw, Walter J.
Publicado: (2021)

Therapeutic Targeting of Innate Immune Receptors Against SARS-CoV-2 Infection
por: Farooq, Mariya, et al.
Publicado: (2022)

NF-kB (p50/p65)-Mediated Pro-Inflammatory microRNA (miRNA) Signaling in Alzheimer's Disease (AD)
por: Lukiw, Walter J.
Publicado: (2022)

Metal-Sulfate Induced Generation of ROS in Human Brain Cells: Detection Using an Isomeric Mixture of 5- and 6-Carboxy-2′,7′-Dichlorofluorescein Diacetate (Carboxy-DCFDA) as a Cell Permeant Tracer
por: Pogue, Aileen I., et al.
Publicado: (2012)

MiRNAs at the Crossroads between Innate Immunity and Cancer: Focus on Macrophages
por: Curtale, Graziella
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vucth723messmmdmdrcur94jmd