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Divergent Metabolomic Signatures of TGFβ2 and TNFα in the Induction of Retinal Epithelial-Mesenchymal Transition

Epithelial-mesenchymal transition (EMT) is a dedifferentiation program in which polarized, differentiated epithelial cells lose their cell-cell adhesions and transform into matrix-producing mesenchymal cells. EMT of retinal pigment epithelial (RPE) cells plays a crucial role in many retinal diseases...

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Detalles Bibliográficos
Autores principales: Ng, Pei Qin, Saint-Geniez, Magali, Kim, Leo A., Shu, Daisy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966219/
https://www.ncbi.nlm.nih.gov/pubmed/36837832
http://dx.doi.org/10.3390/metabo13020213