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Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective

Domain of unknown function (DUF) is a general term for many uncharacterized domains with two distinct features: relatively conservative amino acid sequence and unknown function of the domain. In the Pfam 35.0 database, 4795 (24%) gene families belong to the DUF type, yet, their functions remain to b...

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Detalles Bibliográficos
Autores principales: Lv, Peiyun, Wan, Jinlu, Zhang, Chunting, Hina, Aiman, Al Amin, G M, Begum, Naheeda, Zhao, Tuanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966272/
https://www.ncbi.nlm.nih.gov/pubmed/36835600
http://dx.doi.org/10.3390/ijms24044187