A Comprehensive Structural Analysis of Clostridium botulinum Neurotoxin A Cell-Binding Domain from Different Subtypes

Botulinum neurotoxins (BoNTs) cause flaccid neuromuscular paralysis by cleaving one of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex proteins. BoNTs display high affinity and specificity for neuromuscular junctions, making them one of the most potent neuro...

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Detalles Bibliográficos
Autores principales: Gregory, Kyle S., Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966434/
https://www.ncbi.nlm.nih.gov/pubmed/36828407
http://dx.doi.org/10.3390/toxins15020092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966434/
https://www.ncbi.nlm.nih.gov/pubmed/36828407
http://dx.doi.org/10.3390/toxins15020092

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