Cargando…

Quality by Design Assisted Optimization and Risk Assessment of Black Cohosh Loaded Ethosomal Gel for Menopause: Investigating Different Formulation and Process Variables

Black cohosh (Cimicifuga racemosa) (CR) is a popular herb and is medically lauded for ameliorating myriad symptoms associated with menopause. However, its pharmaceutical limitations and non-availability of a patient-compliant drug delivery approach have precluded its prevalent use. Henceforth, the c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohapatra, Sradhanjali, Mirza, Mohd. Aamir, Ahmad, Sayeed, Farooq, Uzma, Ansari, Mohammad Javed, Kohli, Kanchan, Iqbal, Zeenat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966456/ https://www.ncbi.nlm.nih.gov/pubmed/36839787 http://dx.doi.org/10.3390/pharmaceutics15020465

Ejemplares similares

Benefits of Black Cohosh (Cimicifuga racemosa) for Women Health: An Up-Close and In-Depth Review
por: Mohapatra, Sradhanjali, et al.
Publicado: (2022)

Nanotechnology in Cosmetics and Cosmeceuticals—A Review of Latest Advancements
por: Gupta, Vaibhav, et al.
Publicado: (2022)

In Silico Drug Screening Based Development of Novel Formulations for Onychomycosis Management
por: Fatima, Mahak, et al.
Publicado: (2021)

COVID 19 pandemic challenges and their management: A review of medicines, vaccines, patents and clinical trials with emphasis on psychological health issues
por: Mohapatra, Sradhanjali, et al.
Publicado: (2022)

Ethosomal Gel Formulation of Alpha Phellandrene for the Transdermal Delivery in Gout
por: Valsalan Soba, Sony, et al.
Publicado: (2021)

The Use of Black Cohosh during Pregnancy
por: Van DeWarker, Ely
Publicado: (1873)

Biomedical Application, Patent Repository, Clinical Trial and Regulatory Updates on Hydrogel: An Extensive Review
por: Mohapatra, Sradhanjali, et al.
Publicado: (2021)

A comparative study on the effect of “black cohosh” and “evening primrose oil” on menopausal hot flashes
por: Mehrpooya, Maryam, et al.
Publicado: (2018)

Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation
por: Yu, Zhenwei, et al.
Publicado: (2016)

A Novel Approach of Targeting Linezolid Nanoemulsion for the Management of Lymph Node Tuberculosis
por: Choudhary, Anam, et al.
Publicado: (2022)

Black Cohosh: Insights into its Mechanism(s) of Action
por: Ruhlen, Rachel L., et al.
Publicado: (2008)

Black Cohosh and Liver Toxicity: Is There a Relationship?
por: Muqeet Adnan, Mohammed, et al.
Publicado: (2014)

Black Cohosh Hepatotoxicity with Autoimmune Hepatitis Presentation
por: Franco, Diana L., et al.
Publicado: (2017)

Efficacy of black cohosh (Cimicifuga racemosa L.) in treating early symptoms of menopause: a randomized clinical trial
por: Mohammad-Alizadeh-Charandabi, Sakineh, et al.
Publicado: (2013)

Gene expression analyses on multi-target mode of action of black cohosh in menopausal complaints – a pilot study in rodents
por: Stute, Petra, et al.
Publicado: (2021)

Liposomal and Ethosomal Gels: From Design to Application
por: Sguizzato, Maddalena, et al.
Publicado: (2023)

Ethosomal nanocarriers: the impact of constituents and formulation techniques on ethosomal properties, in vivo studies, and clinical trials
por: Abdulbaqi, Ibrahim M, et al.
Publicado: (2016)

Design and Characterization of an Ethosomal Gel Encapsulating Rosehip Extract
por: Sallustio, Valentina, et al.
Publicado: (2023)

Black Cohosh and St. John's Wort (GYNO-Plus®) for Climacteric Symptoms
por: Chung, Da-Jung, et al.
Publicado: (2007)

Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract
por: Bernacki, Derek T., et al.
Publicado: (2019)

A Preliminary Study on the Effects of Black Cohosh Preparations on Bone Metabolism of Rat Models With GnRH-a-Induced Peri-Menopausal Symptoms
por: Qin, Zhenyue, et al.
Publicado: (2022)

Central Composite Design (CCD) for the Optimisation of Ethosomal Gel Formulation of Punica granatum Extract: In Vitro and In Vivo Evaluations
por: Alam, Prawez, et al.
Publicado: (2022)

Ethosomal Gel for Improving Transdermal Delivery of Thymosin β-4
por: Fu, Xianglei, et al.
Publicado: (2019)

Liver Injury with Features Mimicking Autoimmune Hepatitis following the Use of Black Cohosh
por: Guzman, Grace, et al.
Publicado: (2009)

In Silico Guided Nanoformulation Strategy for Circumvention of Candida albicans Biofilm for Effective Therapy of Candidal Vulvovaginitis
por: Hassan, Nazia, et al.
Publicado: (2023)

Polymeric ethosomal gel loaded with nimodipine: Optimisation, pharmacokinetic and histopathological analysis
por: Moideen Muthu Mohamed, Jamal, et al.
Publicado: (2022)

Isolation of CYP3A4 Inhibitors from the Black Cohosh (Cimicifuga racemosa)
por: Tsukamoto, Sachiko, et al.
Publicado: (2005)

The antiestrogenic effects of black cohosh on BRCA1 and steroid receptors in breast cancer cells
por: Crone, Michael, et al.
Publicado: (2019)

Ethosomal Gel for Topical Administration of Dimethyl Fumarate in the Treatment of HSV-1 Infections
por: Sicurella, Mariaconcetta, et al.
Publicado: (2023)

Severe Hyponatremia Associated with Use of Black Cohosh during Prolonged Labor and Unsuccessful Home Birth
por: Blitz, Matthew J., et al.
Publicado: (2016)

Investigation of anodized titanium implants coated with triterpenoids extracted from black cohosh: an animal study
por: Park, In-Phill, et al.
Publicado: (2014)

Formulation and optimization of nano-sized ethosomes for enhanced transdermal delivery of cromolyn sodium
por: Rakesh, R., et al.
Publicado: (2012)

Raw Materials, Technology, Healthcare Applications, Patent Repository and Clinical Trials on 4D Printing Technology: An Updated Review
por: Khan, Mohammad Sameer, et al.
Publicado: (2022)

Structure-Guided Identification of Black Cohosh (Actaea racemosa) Triterpenoids with In Vitro Activity against Multiple Myeloma
por: Jöhrer, Karin, et al.
Publicado: (2020)

Quality by Design for Development, Optimization and Characterization of Brucine Ethosomal Gel for Skin Cancer Delivery
por: Ismail, Tamer A., et al.
Publicado: (2021)

Ethosomal gel for rectal transmucosal delivery of domperidone: design of experiment, in vitro, and in vivo evaluation
por: Sakran, Wedad, et al.
Publicado: (2022)

Formulative Study and Intracellular Fate Evaluation of Ethosomes and Transethosomes for Vitamin D3 Delivery
por: Costanzo, Manuela, et al.
Publicado: (2021)

Preparation and quality by design assisted (Qb-d) optimization of bioceramic loaded microspheres for periodontal delivery of doxycycline hyclate
por: Jain, Pooja, et al.
Publicado: (2021)

Potential of Lipid-Based Nanocarriers against Two Major Barriers to Drug Delivery—Skin and Blood–Brain Barrier
por: Khan, Mohammad Sameer, et al.
Publicado: (2023)

A Pharmaco-Technical Investigation of Thymoquinone and Peat-Sourced Fulvic Acid Nanoemulgel: A Combination Therapy
por: Khan, Rahmuddin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_k4111a5b6r64rebu86hkrff5tj