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Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS
In this study, a simple and efficient magnetic solid-phase extraction (MSPE) strategy was developed to simultaneously purify and enrich nine mycotoxins in fruits, with the magnetic covalent organic framework nanomaterial Fe(3)O(4)@COF(TAPT–DHTA) as an adsorbent. The Fe(3)O(4)@COF(TAPT–DHTA) was prep...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966527/ https://www.ncbi.nlm.nih.gov/pubmed/36828431 http://dx.doi.org/10.3390/toxins15020117 |
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author | Wang, Jie Huang, Qingwen Guo, Wenbo Guo, Dakai Han, Zheng Nie, Dongxia |
author_facet | Wang, Jie Huang, Qingwen Guo, Wenbo Guo, Dakai Han, Zheng Nie, Dongxia |
author_sort | Wang, Jie |
collection | PubMed |
description | In this study, a simple and efficient magnetic solid-phase extraction (MSPE) strategy was developed to simultaneously purify and enrich nine mycotoxins in fruits, with the magnetic covalent organic framework nanomaterial Fe(3)O(4)@COF(TAPT–DHTA) as an adsorbent. The Fe(3)O(4)@COF(TAPT–DHTA) was prepared by a simple template precipitation polymerization method, using Fe(3)O(4) as magnetic core, and 1,3,5-tris-(4-aminophenyl) triazine (TAPT) and 2,5-dihydroxy terephthalaldehyde (DHTA) as two building units. Fe(3)O(4)@COF(TAPT–DHTA) could effectively capture the targeted mycotoxins by virtue of its abundant hydroxyl groups and aromatic rings. Several key parameters affecting the performance of the MSPE method were studied, including the adsorption solution, adsorption time, elution solvent, volume and time, and the amount of Fe(3)O(4)@COF(TAPT–DHTA) nanomaterial. Under optimized MSPE conditions, followed by analysis with UHPLC–MS/MS, a wide linear range (0.05–200 μg kg(−1)), low limits of detection (0.01–0.5 μg kg(−1)) and satisfactory recovery (74.25–111.75%) were achieved for the nine targeted mycotoxins. The established method was further successfully validated in different kinds of fruit samples. |
format | Online Article Text |
id | pubmed-9966527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99665272023-02-26 Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS Wang, Jie Huang, Qingwen Guo, Wenbo Guo, Dakai Han, Zheng Nie, Dongxia Toxins (Basel) Article In this study, a simple and efficient magnetic solid-phase extraction (MSPE) strategy was developed to simultaneously purify and enrich nine mycotoxins in fruits, with the magnetic covalent organic framework nanomaterial Fe(3)O(4)@COF(TAPT–DHTA) as an adsorbent. The Fe(3)O(4)@COF(TAPT–DHTA) was prepared by a simple template precipitation polymerization method, using Fe(3)O(4) as magnetic core, and 1,3,5-tris-(4-aminophenyl) triazine (TAPT) and 2,5-dihydroxy terephthalaldehyde (DHTA) as two building units. Fe(3)O(4)@COF(TAPT–DHTA) could effectively capture the targeted mycotoxins by virtue of its abundant hydroxyl groups and aromatic rings. Several key parameters affecting the performance of the MSPE method were studied, including the adsorption solution, adsorption time, elution solvent, volume and time, and the amount of Fe(3)O(4)@COF(TAPT–DHTA) nanomaterial. Under optimized MSPE conditions, followed by analysis with UHPLC–MS/MS, a wide linear range (0.05–200 μg kg(−1)), low limits of detection (0.01–0.5 μg kg(−1)) and satisfactory recovery (74.25–111.75%) were achieved for the nine targeted mycotoxins. The established method was further successfully validated in different kinds of fruit samples. MDPI 2023-02-01 /pmc/articles/PMC9966527/ /pubmed/36828431 http://dx.doi.org/10.3390/toxins15020117 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Jie Huang, Qingwen Guo, Wenbo Guo, Dakai Han, Zheng Nie, Dongxia Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS |
title | Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS |
title_full | Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS |
title_fullStr | Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS |
title_full_unstemmed | Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS |
title_short | Fe(3)O(4)@COF(TAPT–DHTA) Nanocomposites as Magnetic Solid-Phase Extraction Adsorbents for Simultaneous Determination of 9 Mycotoxins in Fruits by UHPLC–MS/MS |
title_sort | fe(3)o(4)@cof(tapt–dhta) nanocomposites as magnetic solid-phase extraction adsorbents for simultaneous determination of 9 mycotoxins in fruits by uhplc–ms/ms |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966527/ https://www.ncbi.nlm.nih.gov/pubmed/36828431 http://dx.doi.org/10.3390/toxins15020117 |
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