Inhibition of Enzymatic Acetylation-Mediated Resistance to Plazomicin by Silver Ions

Plazomicin is a recent U.S. Food and Drug Administration (FDA)-approved semisynthetic aminoglycoside. Its structure consists of a sisomicin scaffold modified by adding a 2(S)-hydroxy aminobutyryl group at the N1 position and a hydroxyethyl substituent at the 6′ position. These substitutions produced...

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Detalles Bibliográficos
Autores principales: Ngo, David, Magaña, Angel J., Tran, Tung, Sklenicka, Jan, Phan, Kimberly, Eykholt, Brian, Jimenez, Verónica, Ramirez, María S., Tolmasky, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966628/
https://www.ncbi.nlm.nih.gov/pubmed/37259383
http://dx.doi.org/10.3390/ph16020236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966628/
https://www.ncbi.nlm.nih.gov/pubmed/37259383
http://dx.doi.org/10.3390/ph16020236

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