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Oral Administration of TrkB Agonist, 7, 8–Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin–Induced Vestibular Injury in Guinea Pig

The causes of vestibular dysfunction include the loss of hair cells (HCs), synapses beneath the HCs, and nerve fibers. 7, 8–dihydroxyflavone (DHF) mimics the physiological functions of brain-derived neurotrophic factor. We investigated the effects of the orally-administered DHF in the guinea pig cri...

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Detalles Bibliográficos
Autores principales:	Kinoshita, Makoto, Fujimoto, Chisato, Iwasaki, Shinichi, Kondo, Kenji, Yamasoba, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966733/ https://www.ncbi.nlm.nih.gov/pubmed/36839815 http://dx.doi.org/10.3390/pharmaceutics15020493

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