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Liposomal Delivery of MIW815 (ADU-S100) for Potentiated STING Activation

Stimulator of interferon genes (STING) agonists can improve the anticancer efficacy of immune checkpoint blockade by amplifying tumor immunogenicity. However, the clinical translation of cyclic dinucleotides (CDNs) as STING agonists is hindered by their poor drug-like properties. In this study, we i...

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Detalles Bibliográficos
Autores principales: Ji, Nan, Wang, Minjia, Tan, Chalet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966736/
https://www.ncbi.nlm.nih.gov/pubmed/36839960
http://dx.doi.org/10.3390/pharmaceutics15020638