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Stochastic Modelling of HIV-1 Replication in a CD4 T Cell with an IFN Response

A mathematical model of the human immunodeficiency virus Type 1 (HIV-1) life cycle in CD4 T cells was constructed and calibrated. It describes the activation of the intracellular Type I interferon (IFN-I) response and the IFN-induced suppression of viral replication. The model includes viral replica...

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Detalles Bibliográficos
Autores principales: Sazonov, Igor, Grebennikov, Dmitry, Savinkov, Rostislav, Soboleva, Arina, Pavlishin, Kirill, Meyerhans, Andreas, Bocharov, Gennady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966781/
https://www.ncbi.nlm.nih.gov/pubmed/36851511
http://dx.doi.org/10.3390/v15020296