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Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease
(1) Background: The Modified Sequential Organ Failure Assessment (mSOFA) is an Early Warning Score (EWS) that has proven to be useful in identifying patients at high risk of mortality in prehospital care. The main objective of this study was to evaluate the predictive validity of prehospital mSOFA i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966856/ https://www.ncbi.nlm.nih.gov/pubmed/36826584 http://dx.doi.org/10.3390/jcdd10020088 |
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author | Castro Portillo, Enrique López-Izquierdo, Raúl Castro Villamor, Miguel A. Sanz-García, Ancor Martín-Conty, José L. Polonio-López, Begoña Sánchez-Soberón, Irene del Pozo Vegas, Carlos Durantez-Fernández, Carlos Conty-Serrano, Rosa Martín-Rodríguez, Francisco |
author_facet | Castro Portillo, Enrique López-Izquierdo, Raúl Castro Villamor, Miguel A. Sanz-García, Ancor Martín-Conty, José L. Polonio-López, Begoña Sánchez-Soberón, Irene del Pozo Vegas, Carlos Durantez-Fernández, Carlos Conty-Serrano, Rosa Martín-Rodríguez, Francisco |
author_sort | Castro Portillo, Enrique |
collection | PubMed |
description | (1) Background: The Modified Sequential Organ Failure Assessment (mSOFA) is an Early Warning Score (EWS) that has proven to be useful in identifying patients at high risk of mortality in prehospital care. The main objective of this study was to evaluate the predictive validity of prehospital mSOFA in estimating 2- and 90-day mortality (all-cause) in patients with acute cardiovascular diseases (ACVD), and to compare this validity to that of four other widely-used EWS. (2) Methods: We conducted a prospective, observational, multicentric, ambulance-based study in adults with suspected ACVD who were transferred by ambulance to Emergency Departments (ED). The primary outcome was 2- and 90-day mortality (all-cause in- and out-hospital). The discriminative power of the predictive variable was assessed and evaluated by the area under the curve (AUC) of the receiver operating characteristic (ROC). (3) Results: A total of 1540 patients met the inclusion criteria. The 2- and 90-day mortality rates were 5.3% and 12.7%, respectively. The mSOFA showed the highest AUC of all the evaluated scores for both 2- and 90-day mortality, AUC = 0.943 (0.917–0.968) and AUC = 0.874 (0.847–0.902), respectively. (4) Conclusions: The mSOFA is a quick and easy-to-use EWS with an excellent ability to predict mortality at both 2 and 90 days in patients treated for ACVD, and has proved to be superior to the other EWS evaluated in this study. |
format | Online Article Text |
id | pubmed-9966856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99668562023-02-26 Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease Castro Portillo, Enrique López-Izquierdo, Raúl Castro Villamor, Miguel A. Sanz-García, Ancor Martín-Conty, José L. Polonio-López, Begoña Sánchez-Soberón, Irene del Pozo Vegas, Carlos Durantez-Fernández, Carlos Conty-Serrano, Rosa Martín-Rodríguez, Francisco J Cardiovasc Dev Dis Article (1) Background: The Modified Sequential Organ Failure Assessment (mSOFA) is an Early Warning Score (EWS) that has proven to be useful in identifying patients at high risk of mortality in prehospital care. The main objective of this study was to evaluate the predictive validity of prehospital mSOFA in estimating 2- and 90-day mortality (all-cause) in patients with acute cardiovascular diseases (ACVD), and to compare this validity to that of four other widely-used EWS. (2) Methods: We conducted a prospective, observational, multicentric, ambulance-based study in adults with suspected ACVD who were transferred by ambulance to Emergency Departments (ED). The primary outcome was 2- and 90-day mortality (all-cause in- and out-hospital). The discriminative power of the predictive variable was assessed and evaluated by the area under the curve (AUC) of the receiver operating characteristic (ROC). (3) Results: A total of 1540 patients met the inclusion criteria. The 2- and 90-day mortality rates were 5.3% and 12.7%, respectively. The mSOFA showed the highest AUC of all the evaluated scores for both 2- and 90-day mortality, AUC = 0.943 (0.917–0.968) and AUC = 0.874 (0.847–0.902), respectively. (4) Conclusions: The mSOFA is a quick and easy-to-use EWS with an excellent ability to predict mortality at both 2 and 90 days in patients treated for ACVD, and has proved to be superior to the other EWS evaluated in this study. MDPI 2023-02-17 /pmc/articles/PMC9966856/ /pubmed/36826584 http://dx.doi.org/10.3390/jcdd10020088 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Castro Portillo, Enrique López-Izquierdo, Raúl Castro Villamor, Miguel A. Sanz-García, Ancor Martín-Conty, José L. Polonio-López, Begoña Sánchez-Soberón, Irene del Pozo Vegas, Carlos Durantez-Fernández, Carlos Conty-Serrano, Rosa Martín-Rodríguez, Francisco Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease |
title | Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease |
title_full | Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease |
title_fullStr | Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease |
title_full_unstemmed | Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease |
title_short | Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease |
title_sort | modified sequential organ failure assessment score vs. early warning scores in prehospital care to predict major adverse cardiac events in acute cardiovascular disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966856/ https://www.ncbi.nlm.nih.gov/pubmed/36826584 http://dx.doi.org/10.3390/jcdd10020088 |
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