The Molecular Heterogeneity of Store-Operated Ca(2+) Entry in Vascular Endothelial Cells: The Different roles of Orai1 and TRPC1/TRPC4 Channels in the Transition from Ca(2+)-Selective to Non-Selective Cation Currents

Store-operated Ca(2+) entry (SOCE) is activated in response to the inositol-1,4,5-trisphosphate (InsP(3))-dependent depletion of the endoplasmic reticulum (ER) Ca(2+) store and represents a ubiquitous mode of Ca(2+) influx. In vascular endothelial cells, SOCE regulates a plethora of functions that m...

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Detalles Bibliográficos
Autores principales: Moccia, Francesco, Brunetti, Valentina, Perna, Angelica, Guerra, Germano, Soda, Teresa, Berra-Romani, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967124/
https://www.ncbi.nlm.nih.gov/pubmed/36834672
http://dx.doi.org/10.3390/ijms24043259

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