Cargando…
Functional Importance of the Hydrophobic Residue 362 in Influenza A PB1 Subunit
PB1, acting as the catalytic subunit of the influenza polymerase, has numerous sequentially and structurally conserved regions. It has been observed that the slight modification of residues in PB1 would greatly affect the polymerase activity and even host adaptation ability. Here, we identified a cr...
Autores principales: | Chan, Johnson Jor-Shing, Tang, Yun-Sang, Lo, Chun-Yeung, Shaw, Pang-Chui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967172/ https://www.ncbi.nlm.nih.gov/pubmed/36851609 http://dx.doi.org/10.3390/v15020396 |
Ejemplares similares
-
Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627
por: Ng, Andy Ka-Leung, et al.
Publicado: (2012) -
Interaction between influenza A virus nucleoprotein and PB2 cap-binding domain is mediated by RNA
por: Szeto, Wun-Chung, et al.
Publicado: (2020) -
The PB2 Subunit of the Influenza A Virus RNA Polymerase Is Imported into the Mitochondrial Matrix
por: Long, Joshua C. D., et al.
Publicado: (2016) -
Amino acid substitutions affecting aspartic acid 605 and valine 606 decrease the interaction strength between the influenza virus RNA polymerase PB2 '627' domain and the viral nucleoprotein
por: Hsia, Ho-Pan, et al.
Publicado: (2018) -
Prevalence and clinical significance of mediator complex subunit 12 mutations in 362 Han Chinese samples with uterine leiomyoma
por: Wu, Juan, et al.
Publicado: (2017)