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Drug Delivery Systems in Regenerative Medicine: An Updated Review
Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder their benefits. Moreover, advances in biotechnology resulted in the development of a new generation of mole...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967372/ https://www.ncbi.nlm.nih.gov/pubmed/36840018 http://dx.doi.org/10.3390/pharmaceutics15020695 |
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author | Mansour, Alaa Romani, Maya Acharya, Anirudh Balakrishna Rahman, Betul Verron, Elise Badran, Zahi |
author_facet | Mansour, Alaa Romani, Maya Acharya, Anirudh Balakrishna Rahman, Betul Verron, Elise Badran, Zahi |
author_sort | Mansour, Alaa |
collection | PubMed |
description | Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder their benefits. Moreover, advances in biotechnology resulted in the development of a new generation of molecules with a short half-life that necessitates frequent administration. In this context, controlled release systems are required to enhance treatment efficacy and improve patient compliance. Innovative drug delivery systems are promising tools that protect therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. The present review provides an overview of different approaches used for drug delivery. |
format | Online Article Text |
id | pubmed-9967372 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99673722023-02-26 Drug Delivery Systems in Regenerative Medicine: An Updated Review Mansour, Alaa Romani, Maya Acharya, Anirudh Balakrishna Rahman, Betul Verron, Elise Badran, Zahi Pharmaceutics Review Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder their benefits. Moreover, advances in biotechnology resulted in the development of a new generation of molecules with a short half-life that necessitates frequent administration. In this context, controlled release systems are required to enhance treatment efficacy and improve patient compliance. Innovative drug delivery systems are promising tools that protect therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. The present review provides an overview of different approaches used for drug delivery. MDPI 2023-02-18 /pmc/articles/PMC9967372/ /pubmed/36840018 http://dx.doi.org/10.3390/pharmaceutics15020695 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mansour, Alaa Romani, Maya Acharya, Anirudh Balakrishna Rahman, Betul Verron, Elise Badran, Zahi Drug Delivery Systems in Regenerative Medicine: An Updated Review |
title | Drug Delivery Systems in Regenerative Medicine: An Updated Review |
title_full | Drug Delivery Systems in Regenerative Medicine: An Updated Review |
title_fullStr | Drug Delivery Systems in Regenerative Medicine: An Updated Review |
title_full_unstemmed | Drug Delivery Systems in Regenerative Medicine: An Updated Review |
title_short | Drug Delivery Systems in Regenerative Medicine: An Updated Review |
title_sort | drug delivery systems in regenerative medicine: an updated review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967372/ https://www.ncbi.nlm.nih.gov/pubmed/36840018 http://dx.doi.org/10.3390/pharmaceutics15020695 |
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