Cargando…

Drug Delivery Systems in Regenerative Medicine: An Updated Review

Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder their benefits. Moreover, advances in biotechnology resulted in the development of a new generation of mole...

Descripción completa

Detalles Bibliográficos
Autores principales: Mansour, Alaa, Romani, Maya, Acharya, Anirudh Balakrishna, Rahman, Betul, Verron, Elise, Badran, Zahi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967372/
https://www.ncbi.nlm.nih.gov/pubmed/36840018
http://dx.doi.org/10.3390/pharmaceutics15020695
_version_ 1784897248018038784
author Mansour, Alaa
Romani, Maya
Acharya, Anirudh Balakrishna
Rahman, Betul
Verron, Elise
Badran, Zahi
author_facet Mansour, Alaa
Romani, Maya
Acharya, Anirudh Balakrishna
Rahman, Betul
Verron, Elise
Badran, Zahi
author_sort Mansour, Alaa
collection PubMed
description Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder their benefits. Moreover, advances in biotechnology resulted in the development of a new generation of molecules with a short half-life that necessitates frequent administration. In this context, controlled release systems are required to enhance treatment efficacy and improve patient compliance. Innovative drug delivery systems are promising tools that protect therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. The present review provides an overview of different approaches used for drug delivery.
format Online
Article
Text
id pubmed-9967372
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99673722023-02-26 Drug Delivery Systems in Regenerative Medicine: An Updated Review Mansour, Alaa Romani, Maya Acharya, Anirudh Balakrishna Rahman, Betul Verron, Elise Badran, Zahi Pharmaceutics Review Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder their benefits. Moreover, advances in biotechnology resulted in the development of a new generation of molecules with a short half-life that necessitates frequent administration. In this context, controlled release systems are required to enhance treatment efficacy and improve patient compliance. Innovative drug delivery systems are promising tools that protect therapeutic proteins and peptides against proteolytic degradation where controlled delivery is achievable. The present review provides an overview of different approaches used for drug delivery. MDPI 2023-02-18 /pmc/articles/PMC9967372/ /pubmed/36840018 http://dx.doi.org/10.3390/pharmaceutics15020695 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mansour, Alaa
Romani, Maya
Acharya, Anirudh Balakrishna
Rahman, Betul
Verron, Elise
Badran, Zahi
Drug Delivery Systems in Regenerative Medicine: An Updated Review
title Drug Delivery Systems in Regenerative Medicine: An Updated Review
title_full Drug Delivery Systems in Regenerative Medicine: An Updated Review
title_fullStr Drug Delivery Systems in Regenerative Medicine: An Updated Review
title_full_unstemmed Drug Delivery Systems in Regenerative Medicine: An Updated Review
title_short Drug Delivery Systems in Regenerative Medicine: An Updated Review
title_sort drug delivery systems in regenerative medicine: an updated review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967372/
https://www.ncbi.nlm.nih.gov/pubmed/36840018
http://dx.doi.org/10.3390/pharmaceutics15020695
work_keys_str_mv AT mansouralaa drugdeliverysystemsinregenerativemedicineanupdatedreview
AT romanimaya drugdeliverysystemsinregenerativemedicineanupdatedreview
AT acharyaanirudhbalakrishna drugdeliverysystemsinregenerativemedicineanupdatedreview
AT rahmanbetul drugdeliverysystemsinregenerativemedicineanupdatedreview
AT verronelise drugdeliverysystemsinregenerativemedicineanupdatedreview
AT badranzahi drugdeliverysystemsinregenerativemedicineanupdatedreview