Cargando…

Inositol in Disease and Development: Roles of Catabolism via myo-Inositol Oxygenase in Drosophila melanogaster

Inositol depletion has been associated with diabetes and related complications. Increased inositol catabolism, via myo-inositol oxygenase (MIOX), has been implicated in decreased renal function. This study demonstrates that the fruit fly Drosophila melanogaster catabolizes myo-inositol via MIOX. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Contreras, Altagracia, Jones, Melissa K., Eldon, Elizabeth D., Klig, Lisa S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967586/ https://www.ncbi.nlm.nih.gov/pubmed/36835596 http://dx.doi.org/10.3390/ijms24044185

Ejemplares similares

Regulated inositol synthesis is critical for balanced metabolism and development in Drosophila melanogaster
por: Rivera, Maria J., et al.
Publicado: (2021)

Disruption of INOS, a Gene Encoding myo-Inositol Phosphate Synthase, Causes Male Sterility in Drosophila melanogaster
por: Jackson, Natasha A. M., et al.
Publicado: (2018)

Computational modeling and in silico analysis of differential regulation of myo-inositol catabolic enzymes in Cryptococcus neoformans
por: Mackenzie, Emalee A, et al.
Publicado: (2008)

Myo-inositol oxygenase is important for the removal of excess myo-inositol from syncytia induced by Heterodera schachtii in Arabidopsis roots
por: Siddique, Shahid, et al.
Publicado: (2014)

Evaluation of the effect of Retrograde Intrarenal Surgery with Myo-Inositol Oxygenase
por: Mertoglu, Cuma, et al.
Publicado: (2018)

Effects of myo-inositol plus alpha-lactalbumin in myo-inositol-resistant PCOS women
por: Montanino Oliva, Mario, et al.
Publicado: (2018)

myo-Inositol Oxygenase is Required for Responses to Low Energy Conditions in Arabidopsis thaliana
por: Alford, Shannon R., et al.
Publicado: (2012)

Myo–inositol Oxygenase as a Novel Marker in the Diagnosis of Acute Kidney Injury
por: Mertoglu, Cuma, et al.
Publicado: (2018)

Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate
por: Bizzarri, Mariano, et al.
Publicado: (2016)

Stereoselective Voltammetric Biosensor for Myo-Inositol and D-Chiro-Inositol Recognition
por: Tortolini, Cristina, et al.
Publicado: (2023)

Role of myo-inositol during skotomorphogenesis in Arabidopsis
por: Sharma, Naveen, et al.
Publicado: (2020)

Myo-inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes
por: Sharma, Isha, et al.
Publicado: (2020)

Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors
por: Sharma, Isha, et al.
Publicado: (2020)

2-Benzyl-myo-inositol monohydrate
por: Fröhlich, Richard F. G., et al.
Publicado: (2009)

The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes
por: Pintaudi, Basilio, et al.
Publicado: (2016)

Inositols affect the mating circadian rhythm of Drosophila melanogaster
por: Sakata, Kazuki, et al.
Publicado: (2015)

Harnessing (13)C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR
por: Harmel, Robert K., et al.
Publicado: (2019)

Inhibited inositol monophosphatase and decreased myo‐inositol concentration improve wasting in skeletal muscles
por: Lee, Ji‐Hyung, et al.
Publicado: (2020)

Valproate regulates inositol synthesis by reducing expression of myo-inositol-3-phosphate synthase
por: Case, Kendall C., et al.
Publicado: (2023)

Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review
por: Bizzarri, Mariano, et al.
Publicado: (2023)

Myo-Inositol in the Treatment of Teenagers Affected by PCOS
por: Pkhaladze, Lali, et al.
Publicado: (2016)

Hysteresis in myo‐inositol utilization by Salmonella Typhimurium
por: Hellinckx, Jessica, et al.
Publicado: (2016)

Myo-D-inositol Trisphosphate Signalling in Oomycetes
por: Nair, Indu Muraleedharan, et al.
Publicado: (2022)

Down-regulation of the myo-inositol oxygenase gene family has no effect on cell wall composition in Arabidopsis
por: Endres, Stefanie, et al.
Publicado: (2011)

Inositol-phosphodihydroceramides in the periodontal pathogen Tannerella forsythia: Structural analysis and incorporation of exogenous myo-inositol
por: Megson, Zoë Anne, et al.
Publicado: (2015)

Effects of Inositol Hexaphosphate and Myo-Inositol Administration in Breast Cancer Patients during Adjuvant Chemotherapy
por: Amabile, Maria Ida, et al.
Publicado: (2021)

Comparing the Efficacy of Myo-Inositol Plus α-Lactalbumin vs. Myo-Inositol Alone on Reproductive and Metabolic Disturbances of Polycystic Ovary Syndrome
por: Kamenov, Zdravko, et al.
Publicado: (2023)

Cloning of Glucuronokinase from Arabidopsis thaliana, the Last Missing Enzyme of the myo-Inositol Oxygenase Pathway to Nucleotide Sugars
por: Pieslinger, Anja Maria, et al.
Publicado: (2010)

Genome-wide analysis of Myo-inositol oxygenase gene family in tomato reveals their involvement in ascorbic acid accumulation
por: Munir, Shoaib, et al.
Publicado: (2020)

Myo‐inositol oxygenase (MIOX) accelerated inflammation in the model of infection‐induced cardiac dysfunction by NLRP3 inflammasome
por: Zhou, Wenjun, et al.
Publicado: (2023)

PCOS and Inositols: Controversial Results and Necessary Clarifications. Basic Differences Between D-Chiro and Myo-Inositol
por: Monastra, Giovanni, et al.
Publicado: (2021)

Stable Isotopomers of myo-Inositol Uncover a Complex MINPP1-Dependent Inositol Phosphate Network
por: Nguyen Trung, Minh, et al.
Publicado: (2022)

Management of polycystic ovary syndrome among Indian women using myo‐inositol and D-chiro-inositol
por: Vyas, Lila, et al.
Publicado: (2022)

Myo-inositol reduces β-catenin activation in colitis
por: Bradford, Emily M, et al.
Publicado: (2017)

Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol
por: Verner, Zdeněk, et al.
Publicado: (2021)

Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs
por: Hostachy, Sarah, et al.
Publicado: (2023)

Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human Diseases
por: Chhetri, Dhani Raj
Publicado: (2019)

The role of hydrogen bonding in the incommensurate modulation of myo-inositol camphor ketal
por: Savic, Viktor, et al.
Publicado: (2021)

The “Asthma-Polycystic Ovary Overlap Syndrome” and the Therapeutic Role of Myo-Inositol
por: Guarnieri, Gabriella, et al.
Publicado: (2023)

Comparative Genomics of Pneumocystis Species Suggests the Absence of Genes for myo-Inositol Synthesis and Reliance on Inositol Transport and Metabolism
por: Porollo, Aleksey, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1c5fsf8eckpsov8i3026vsolqn