ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation

The present study proposed the synthesis of a novel acridine derivative not yet described in the literature, chemical characterization by NMR, MS, and IR, followed by investigations of its antileishmanial potential. In vitro assays were performed to assess its antileishmanial activity against L. ama...

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Detalles Bibliográficos
Autores principales: Albino, Sonaly Lima, da Silva Moura, Willian Charles, dos Reis, Malu Maria Lucas, Sousa, Gleyton Leonel Silva, da Silva, Pablo Rayff, de Oliveira, Mayara Gabriele Carvalho, Borges, Tatiana Karla dos Santos, Albuquerque, Lucas Fraga Friaça, de Almeida, Sinara Mônica Vitalino, de Lima, Maria do Carmo Alves, Kuckelhaus, Selma Aparecida Souza, Nascimento, Igor José dos Santos, Junior, Francisco Jaime Bezerra Mendonca, da Silva, Teresinha Gonçalves, de Moura, Ricardo Olímpio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967605/
https://www.ncbi.nlm.nih.gov/pubmed/37259353
http://dx.doi.org/10.3390/ph16020204

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