OAT3 Participates in Drug–Drug Interaction between Bentysrepinine and Entecavir through Interactions with M8—A Metabolite of Bentysrepinine—In Rats and Humans In Vitro

Bentysrepinine (Y101) is a novel phenylalanine dipeptide for the treatment of hepatitis B virus. Renal excretion played an important role in the elimination of Y101 and its metabolites, M8 and M9, in healthy Chinese subjects, although the molecular mechanisms of renal excretion and potential drug–dr...

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Detalles Bibliográficos
Autores principales: Zhang, Aijie, Yang, Fanlong, Yuan, Yang, Li, Cai, Huo, Xiaokui, Liu, Jing, Zhou, Shenzhi, Li, Wei, Zhang, Na, Liu, Jianfeng, Dong, Shiqi, Fan, Huirong, Peng, Ying, Zheng, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967645/
https://www.ncbi.nlm.nih.gov/pubmed/36838982
http://dx.doi.org/10.3390/molecules28041995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967645/
https://www.ncbi.nlm.nih.gov/pubmed/36838982
http://dx.doi.org/10.3390/molecules28041995

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