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Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review

Patients under renal replacement therapy (RRT) often show oral problems, including dry mouth, periodontal and dental diseases. This systematic review aimed to evaluate the caries burden in patients on RRT. Therefore, a systematic literature search based on the databases PubMed, Web of Science and Sc...

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Autores principales: Kreher, Deborah, Ernst, Bero Luke Vincent, Ziebolz, Dirk, Haak, Rainer, de Fallois, Jonathan, Ebert, Thomas, Schmalz, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967680/
https://www.ncbi.nlm.nih.gov/pubmed/36836050
http://dx.doi.org/10.3390/jcm12041507
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author Kreher, Deborah
Ernst, Bero Luke Vincent
Ziebolz, Dirk
Haak, Rainer
de Fallois, Jonathan
Ebert, Thomas
Schmalz, Gerhard
author_facet Kreher, Deborah
Ernst, Bero Luke Vincent
Ziebolz, Dirk
Haak, Rainer
de Fallois, Jonathan
Ebert, Thomas
Schmalz, Gerhard
author_sort Kreher, Deborah
collection PubMed
description Patients under renal replacement therapy (RRT) often show oral problems, including dry mouth, periodontal and dental diseases. This systematic review aimed to evaluate the caries burden in patients on RRT. Therefore, a systematic literature search based on the databases PubMed, Web of Science and Scopus was performed by two independent individuals in August 2022. Search terms were: “caries” AND “dialysis”, “caries” AND “renal replacement therapy”, “caries” AND “kidney”. The systematic process was complemented by manual search. Studies on adult patients (age ≥ 18 years), treated by any form of RRT and explicitly reporting caries prevalence or incidence were checked for their eligibility and subsequently analyzed qualitatively. For all included studies, a quality appraisal was applied. From the systematic search, 653 studies were identified, of which 33 clinical investigations were included in the qualitative analysis. The majority (31 studies) of all included patients underwent hemodialysis (HD), with a sample size between 28 and 512 participants. Eleven studies investigated a healthy control group. Oral examinations were heterogeneous across studies; the caries burden was primarily assessed by decayed-(D-T), missing- and filled-teeth index (DMF-T). The number of decayed teeth ranged between 0.7 and 3.87 across studies. Only six out of these 11 studies found significant differences in caries prevalence/incidence between RRT and controls, whereby only four studies confirmed worse caries burden in RRT individuals. No information was provided on caries stadium (initial caries, advanced caries, invasive treatment need), caries activity or location (e.g., root caries) across studies. Most of the included studies were assessed to be of moderate quality. In conclusion, patients on RRT suffer from a high prevalence of dental caries. Alongside a need for further research in the field, improved, multidisciplinary, patient-centered dental care concepts are required to support dental and overall oral health in individuals on RRT.
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spelling pubmed-99676802023-02-27 Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review Kreher, Deborah Ernst, Bero Luke Vincent Ziebolz, Dirk Haak, Rainer de Fallois, Jonathan Ebert, Thomas Schmalz, Gerhard J Clin Med Review Patients under renal replacement therapy (RRT) often show oral problems, including dry mouth, periodontal and dental diseases. This systematic review aimed to evaluate the caries burden in patients on RRT. Therefore, a systematic literature search based on the databases PubMed, Web of Science and Scopus was performed by two independent individuals in August 2022. Search terms were: “caries” AND “dialysis”, “caries” AND “renal replacement therapy”, “caries” AND “kidney”. The systematic process was complemented by manual search. Studies on adult patients (age ≥ 18 years), treated by any form of RRT and explicitly reporting caries prevalence or incidence were checked for their eligibility and subsequently analyzed qualitatively. For all included studies, a quality appraisal was applied. From the systematic search, 653 studies were identified, of which 33 clinical investigations were included in the qualitative analysis. The majority (31 studies) of all included patients underwent hemodialysis (HD), with a sample size between 28 and 512 participants. Eleven studies investigated a healthy control group. Oral examinations were heterogeneous across studies; the caries burden was primarily assessed by decayed-(D-T), missing- and filled-teeth index (DMF-T). The number of decayed teeth ranged between 0.7 and 3.87 across studies. Only six out of these 11 studies found significant differences in caries prevalence/incidence between RRT and controls, whereby only four studies confirmed worse caries burden in RRT individuals. No information was provided on caries stadium (initial caries, advanced caries, invasive treatment need), caries activity or location (e.g., root caries) across studies. Most of the included studies were assessed to be of moderate quality. In conclusion, patients on RRT suffer from a high prevalence of dental caries. Alongside a need for further research in the field, improved, multidisciplinary, patient-centered dental care concepts are required to support dental and overall oral health in individuals on RRT. MDPI 2023-02-14 /pmc/articles/PMC9967680/ /pubmed/36836050 http://dx.doi.org/10.3390/jcm12041507 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kreher, Deborah
Ernst, Bero Luke Vincent
Ziebolz, Dirk
Haak, Rainer
de Fallois, Jonathan
Ebert, Thomas
Schmalz, Gerhard
Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review
title Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review
title_full Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review
title_fullStr Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review
title_full_unstemmed Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review
title_short Prevalence of Dental Caries in Patients on Renal Replacement Therapy—A Systematic Review
title_sort prevalence of dental caries in patients on renal replacement therapy—a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967680/
https://www.ncbi.nlm.nih.gov/pubmed/36836050
http://dx.doi.org/10.3390/jcm12041507
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