Cargando…

RNA Expression Signatures of Intracranial Aneurysm Growth Trajectory Identified in Circulating Whole Blood

After detection, identifying which intracranial aneurysms (IAs) will rupture is imperative. We hypothesized that RNA expression in circulating blood reflects IA growth rate as a surrogate of instability and rupture risk. To this end, we performed RNA sequencing on 66 blood samples from IA patients,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poppenberg, Kerry E., Chien, Aichi, Santo, Briana A., Baig, Ammad A., Monteiro, Andre, Dmytriw, Adam A., Burkhardt, Jan-Karl, Mokin, Maxim, Snyder, Kenneth V., Siddiqui, Adnan H., Tutino, Vincent M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967913/ https://www.ncbi.nlm.nih.gov/pubmed/36836499 http://dx.doi.org/10.3390/jpm13020266

Ejemplares similares

Identification of Circulating Gene Expression Signatures of Intracranial Aneurysm in Peripheral Blood Mononuclear Cells
por: Tutino, Vincent M., et al.
Publicado: (2021)

Hemodynamic Analysis Shows High Wall Shear Stress Is Associated with Intraoperatively Observed Thin Wall Regions of Intracranial Aneurysms
por: Veeturi, Sricharan S., et al.
Publicado: (2022)

Circulating neutrophil transcriptome may reveal intracranial aneurysm signature
por: Tutino, Vincent M., et al.
Publicado: (2018)

Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium
por: Poppenberg, Kerry E., et al.
Publicado: (2019)

Aberrant Whole Blood Gene Expression in the Lumen of Human Intracranial Aneurysms
por: Tutino, Vincent M., et al.
Publicado: (2021)

Biomarkers from circulating neutrophil transcriptomes have potential to detect unruptured intracranial aneurysms
por: Tutino, Vincent M., et al.
Publicado: (2018)

An Image-Based Workflow for Objective Vessel Wall Enhancement Quantification in Intracranial Aneurysms
por: Veeturi, Sricharan S., et al.
Publicado: (2021)

Classification models using circulating neutrophil transcripts can detect unruptured intracranial aneurysm
por: Poppenberg, Kerry E., et al.
Publicado: (2020)

Whole blood transcriptome biomarkers of unruptured intracranial aneurysm
por: Poppenberg, Kerry E., et al.
Publicado: (2020)

Epigenetic landscapes of intracranial aneurysm risk haplotypes implicate enhancer function of endothelial cells and fibroblasts in dysregulated gene expression
por: Poppenberg, Kerry E., et al.
Publicado: (2021)

Aneurysm risk metrics and hemodynamics are associated with greater vessel wall enhancement in intracranial aneurysms
por: Veeturi, Sricharan S., et al.
Publicado: (2021)

Techniques in distal access of wide-necked giant intracranial aneurysms during treatment with flow diversion
por: Kan, Peter, et al.
Publicado: (2015)

Improving accuracy for finite element modeling of endovascular coiling of intracranial aneurysm
por: Damiano, Robert J., et al.
Publicado: (2019)

Use of patient specific 3D printed neurovascular phantoms to simulate mechanical thrombectomy
por: Sommer, Kelsey N., et al.
Publicado: (2021)

Ruptured mycotic cerebral aneurysm development from pseudoocclusion due to septic embolism
por: Sorkin, Grant C., et al.
Publicado: (2013)

Isolation of RNA from Acute Ischemic Stroke Clots Retrieved by Mechanical Thrombectomy
por: Tutino, Vincent M., et al.
Publicado: (2021)

Identification of intima-to-media signals for flow-induced vascular remodeling using correlative gene expression analysis
por: Kolega, John, et al.
Publicado: (2021)

Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes
por: Poppenberg, Kerry E., et al.
Publicado: (2021)

The Use of Flow Diversion for the Treatment of Intracranial Aneurysms: Expansion of Indications
por: Brouillard, Adam M, et al.
Publicado: (2016)

The effect of aneurysm geometry on the intra-aneurysmal flow condition
por: Tateshima, Satoshi, et al.
Publicado: (2010)

Analysis of chromatin data supports a role for CD14+ monocytes/macrophages in mediating genetic risk for juvenile idiopathic arthritis
por: Crinzi, Elizabeth A., et al.
Publicado: (2022)

Prospective study on embolization of intracranial aneurysms with the pipeline device: the PREMIER study 1 year results
por: Hanel, Ricardo A, et al.
Publicado: (2020)

Endothelial Nitric Oxide Synthase and Superoxide Mediate Hemodynamic Initiation of Intracranial Aneurysms
por: Liaw, Nicholas, et al.
Publicado: (2014)

Revascularization Outcome Prediction for A Direct Aspiration-First Pass Technique (ADAPT) from Pre-Treatment Imaging and Machine Learning
por: Patel, Tatsat R., et al.
Publicado: (2021)

Circulating microRNAs in patients with intracranial aneurysms
por: Meeuwsen, John A. L., et al.
Publicado: (2017)

Quantitative comparison of the dynamic flow waveform changes in 12 ruptured and 29 unruptured ICA–ophthalmic artery aneurysms
por: Chien, Aichi, et al.
Publicado: (2013)

A Critical Role for Proinflammatory Behavior of Smooth Muscle Cells in Hemodynamic Initiation of Intracranial Aneurysm
por: Mandelbaum, Max, et al.
Publicado: (2013)

Neovascularization in Human Intracranial Atherosclerotic In-Stent Restenosis
por: Feng, Yiding, et al.
Publicado: (2021)

Treatment of ruptured intracranial aneurysms yesterday and now
por: Hammer, Alexander, et al.
Publicado: (2017)

Endovascular treatment of unruptured posterior circulation intracranial aneurysms
por: Lv, Xianli, et al.
Publicado: (2016)

Ruptured Intracranial Aneurysms
por: McCaughey, W. T. E.
Publicado: (1956)

An overview of intracranial aneurysms
por: Keedy, Alexander
Publicado: (2006)

Intracranial Arterial Aneurysms
por: Brody, Bernard S.
Publicado: (1944)

Familial Intracranial Aneurysm
por: Ammar, Ahmed S.
Publicado: (2016)

Prospective study on embolization of intracranial aneurysms with the pipeline device (PREMIER study): 3-year results with the application of a flow diverter specific occlusion classification
por: Hanel, Ricardo A, et al.
Publicado: (2023)

Cluster headache and intracranial aneurysm
por: Valença, Marcelo Moraes, et al.
Publicado: (2007)

Higher risk of intracranial aneurysms and subarachnoid haemorrhage in siblings of families with intracranial aneurysms
por: Zuurbier, CCM, et al.
Publicado: (2019)

Circulation remodeling after flow diversion of an anterior communicating artery aneurysm: A case report
por: Withers, James, et al.
Publicado: (2023)

The risk of intravenous thrombolysis-induced intracranial hemorrhage in Taiwanese patients with unruptured intracranial aneurysm
por: Chiu, Wei Ting, et al.
Publicado: (2017)

Multiple Anterior and Posterior Circulation Intracranial Fenestrations presenting With Aneurysmal Subarachnoid Hemorrhage
por: Scranton, Robert A, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_geafkfj45f8nv5br0bl3dbhs74