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Harnessing the Power of Venomous Animal-Derived Toxins against COVID-19

Animal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During the COVID-19 pandemic, there was observed an...

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Detalles Bibliográficos
Autores principales: Oliveira, Isadora, Ferreira, Isabela, Jacob, Beatriz, Cardenas, Kiara, Cerni, Felipe, Baia-da-Silva, Djane, Arantes, Eliane, Monteiro, Wuelton, Pucca, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967918/
https://www.ncbi.nlm.nih.gov/pubmed/36828473
http://dx.doi.org/10.3390/toxins15020159
Descripción
Sumario:Animal-derived venoms are complex mixtures of toxins triggering important biological effects during envenomings. Although venom-derived toxins are known for their potential of causing harm to victims, toxins can also act as pharmacological agents. During the COVID-19 pandemic, there was observed an increase in in-depth studies on antiviral agents, and since, to date, there has been no completely effective drug against the global disease. This review explores the crosstalk of animal toxins and COVID-19, aiming to map potential therapeutic agents derived from venoms (e.g., bees, snakes, scorpions, etc.) targeting COVID-19.