Transferability of Published Population Pharmacokinetic Models for Apixaban and Rivaroxaban to Subjects with Obesity Treated for Venous Thromboembolism: A Systematic Review and External Evaluations

Apixaban and rivaroxaban have first-line use for many patients needing anticoagulation for venous thromboembolism (VTE). The pharmacokinetics of these drugs in non-obese subjects have been extensively studied, and, while changes in pharmacokinetics have been documented in obese patients, data remain...

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Detalles Bibliográficos
Autores principales: Leven, Cyril, Ménard, Pauline, Gouin-Thibault, Isabelle, Ballerie, Alice, Lacut, Karine, Ollier, Edouard, Théreaux, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967935/
https://www.ncbi.nlm.nih.gov/pubmed/36839986
http://dx.doi.org/10.3390/pharmaceutics15020665

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