Multicomponent Domino Cyclization of Ethyl Trifluoropyruvate with Methyl Ketones and Amino Alcohols as A New Way to γ-Lactam Annulated Oxazacycles

A new route to bicyclic γ-lactams was found, which was proposed as a three-component cyclization of ethyl trifluoropyruvate with methyl ketones and 1,2-, 1,3-amino alcohols. As a result, a series of trifluoromethyl-substituted tetrahydropyrrolo [2,1-b]oxazol-5-ones and tetrahydropyrrolo[2,1-b][1,3]o...

Descripción completa

Detalles Bibliográficos
Autores principales: Goryaeva, Marina V., Fefelova, Olesya A., Burgart, Yanina V., Ezhikova, Marina A., Kodess, Mikhail I., Slepukhin, Pavel A., Gaviko, Vasily S., Saloutin, Victor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967980/
https://www.ncbi.nlm.nih.gov/pubmed/36838972
http://dx.doi.org/10.3390/molecules28041983

Ejemplares similares

Ejemplares similares