N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling

N-acetylcysteine (NAC) is an antioxidant that prevents tumor necrosis factor (TNF)-α-induced cell death, but it also acts as a pro-oxidant, promoting reactive oxygen species independent apoptosis. Although there is plausible preclinical evidence for the use of NAC in the treatment of psychiatric dis...

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Detalles Bibliográficos
Autores principales: Sakai, Mai, Yu, Zhiqian, Taniguchi, Masayuki, Picotin, Rosanne, Oyama, Nanami, Stellwagen, David, Ono, Chiaki, Kikuchi, Yoshie, Matsui, Ko, Nakanishi, Miharu, Yoshii, Hatsumi, Furuyashiki, Tomoyuki, Abe, Takaaki, Tomita, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968039/
https://www.ncbi.nlm.nih.gov/pubmed/36835209
http://dx.doi.org/10.3390/ijms24043798

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