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Molecular Dynamics Simulation of the Complex of PDE5 and Evodiamine

Alzheimer’s disease is an irreversible neurological disorder for which there are no effective small molecule therapeutics. A phosphodiesterase 5 (PDE5) inhibitor is a candidate medicine for the treatment of Alzheimer’s disease. Rutaecarpine, an indole alkaloid found in Euodiae Fructus, has inhibitor...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Ayame, Nakajima, Motokuni, Noguchi, Yoh, Morikawa, Ryota, Matsuo, Yukiko, Takasu, Masako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968203/ https://www.ncbi.nlm.nih.gov/pubmed/36836935 http://dx.doi.org/10.3390/life13020578

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