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PDGF gene expression and p53 alterations contribute to the biology of diffuse astrocytic gliomas

Diffuse, histologically lower grade astrocytomas of adults (LGAs) are classified based on the mutational status of the isocitrate dehydrogenase (IDH) genes. While wild-type (WT) LGAs often evolve quickly to glioblastoma (GBM), mutant tumors typically follow an indolent course. To find possible effec...

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Detalles Bibliográficos
Autores principales:	Kumar, Mehul, Meode, Mathieu, Blough, Michael, Cairncross, Gregory, Bose, Pinaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968280/ https://www.ncbi.nlm.nih.gov/pubmed/36841881 http://dx.doi.org/10.1038/s41525-023-00351-2

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