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Markedly divergent effects of Ouabain on a Temozolomide-resistant (T98G) vs. a Temozolomide-sensitive (LN229) Glioblastoma cell line

BACKGROUND: Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor prognosis. GMB are highly recurrent mainly because of radio- and chemoresistance. Radiotherapy with Temozolomide (TMZ) is until today the golden standard adjuvant therapy, however, the optimal treatment of...

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Detalles Bibliográficos
Autores principales: Weidemann, Heidrun, Feger, Daniel, Ehlert, Jan E., Menger, Marcus M., Krempien, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968366/
https://www.ncbi.nlm.nih.gov/pubmed/36840822
http://dx.doi.org/10.1007/s12672-023-00633-2