Cargando…

Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers

INTRODUCTION: This in vitro study aimed to evaluate the chemical composition, water solubility, radiopacity, pH, electrical conductivity and cytotoxicity of four different root canal sealers. METHODS AND MATERIALS: Four materials were tested including an epoxy resin-based sealer (AH-Plus), a calcium...

Descripción completa

Detalles Bibliográficos
Autores principales: Borges, Alvaro Henrique, Guedes, Orlando Aguirre, Pereira, Thiago Machado, Guapo-Pavarina, Rodrigo, da Rosa, Welligton Luiz de Oliveira, Piva, Evandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Center for Endodontic Research 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968391/
https://www.ncbi.nlm.nih.gov/pubmed/36855442
http://dx.doi.org/10.22037/iej.v14i2.21666
_version_ 1784897495958028288
author Borges, Alvaro Henrique
Guedes, Orlando Aguirre
Pereira, Thiago Machado
Guapo-Pavarina, Rodrigo
da Rosa, Welligton Luiz de Oliveira
Piva, Evandro
author_facet Borges, Alvaro Henrique
Guedes, Orlando Aguirre
Pereira, Thiago Machado
Guapo-Pavarina, Rodrigo
da Rosa, Welligton Luiz de Oliveira
Piva, Evandro
author_sort Borges, Alvaro Henrique
collection PubMed
description INTRODUCTION: This in vitro study aimed to evaluate the chemical composition, water solubility, radiopacity, pH, electrical conductivity and cytotoxicity of four different root canal sealers. METHODS AND MATERIALS: Four materials were tested including an epoxy resin-based sealer (AH-Plus), a calcium silicate-based sealer (MTA Fillapex), a calcium hydroxide-based sealer (Sealapex) and a zinc-oxide-eugenol-based sealer (Endofill). The materials were submitted to energy-dispersive x-ray microanalysis for elemental chemical composition. Solubility and radiopacity were evaluated according to ANSI/ADA. The pH and electrical conductivity were measured at different periods of time. L929 immortalized mouse fibroblast line were used for cytotoxicity evaluation. Statistical analyses were carried out using the ANOVA and Tukey’s test. RESULTS: The main elements were found to be silicon and calcium in MTA Fillapex, calcium and bismuth in Sealapex, zirconium and tungsten in AH-Plus and zinc and bismuth in Endofill. Sealapex had the highest value for solubility (P<0.05), AH-Plus showed the highest radiopacity value (P<0.05) while MTA Fillapex had the highest pH and electrical conductivity values (P<0.05). AH-Plus showed the highest rate of cell viability (P<0.05). CONCLUSION: Based on the results of this in vitro study, it was possible to conclude that Endofill and Sealpex did not meet the requirements for water solubility. The tested sealers were alkaline and showed radiopacity in accordance with ANSI/ADA standards. AH-Plus showed to be less cytotoxic than other tested root canal sealers.
format Online
Article
Text
id pubmed-9968391
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Iranian Center for Endodontic Research
record_format MEDLINE/PubMed
spelling pubmed-99683912023-02-27 Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers Borges, Alvaro Henrique Guedes, Orlando Aguirre Pereira, Thiago Machado Guapo-Pavarina, Rodrigo da Rosa, Welligton Luiz de Oliveira Piva, Evandro Iran Endod J Original Article INTRODUCTION: This in vitro study aimed to evaluate the chemical composition, water solubility, radiopacity, pH, electrical conductivity and cytotoxicity of four different root canal sealers. METHODS AND MATERIALS: Four materials were tested including an epoxy resin-based sealer (AH-Plus), a calcium silicate-based sealer (MTA Fillapex), a calcium hydroxide-based sealer (Sealapex) and a zinc-oxide-eugenol-based sealer (Endofill). The materials were submitted to energy-dispersive x-ray microanalysis for elemental chemical composition. Solubility and radiopacity were evaluated according to ANSI/ADA. The pH and electrical conductivity were measured at different periods of time. L929 immortalized mouse fibroblast line were used for cytotoxicity evaluation. Statistical analyses were carried out using the ANOVA and Tukey’s test. RESULTS: The main elements were found to be silicon and calcium in MTA Fillapex, calcium and bismuth in Sealapex, zirconium and tungsten in AH-Plus and zinc and bismuth in Endofill. Sealapex had the highest value for solubility (P<0.05), AH-Plus showed the highest radiopacity value (P<0.05) while MTA Fillapex had the highest pH and electrical conductivity values (P<0.05). AH-Plus showed the highest rate of cell viability (P<0.05). CONCLUSION: Based on the results of this in vitro study, it was possible to conclude that Endofill and Sealpex did not meet the requirements for water solubility. The tested sealers were alkaline and showed radiopacity in accordance with ANSI/ADA standards. AH-Plus showed to be less cytotoxic than other tested root canal sealers. Iranian Center for Endodontic Research 2019 /pmc/articles/PMC9968391/ /pubmed/36855442 http://dx.doi.org/10.22037/iej.v14i2.21666 Text en https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.(https://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Original Article
Borges, Alvaro Henrique
Guedes, Orlando Aguirre
Pereira, Thiago Machado
Guapo-Pavarina, Rodrigo
da Rosa, Welligton Luiz de Oliveira
Piva, Evandro
Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers
title Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers
title_full Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers
title_fullStr Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers
title_full_unstemmed Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers
title_short Evaluation of Selective Physicochemical and Biological Properties of Different Root Canal Sealers
title_sort evaluation of selective physicochemical and biological properties of different root canal sealers
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968391/
https://www.ncbi.nlm.nih.gov/pubmed/36855442
http://dx.doi.org/10.22037/iej.v14i2.21666
work_keys_str_mv AT borgesalvarohenrique evaluationofselectivephysicochemicalandbiologicalpropertiesofdifferentrootcanalsealers
AT guedesorlandoaguirre evaluationofselectivephysicochemicalandbiologicalpropertiesofdifferentrootcanalsealers
AT pereirathiagomachado evaluationofselectivephysicochemicalandbiologicalpropertiesofdifferentrootcanalsealers
AT guapopavarinarodrigo evaluationofselectivephysicochemicalandbiologicalpropertiesofdifferentrootcanalsealers
AT darosawelligtonluizdeoliveira evaluationofselectivephysicochemicalandbiologicalpropertiesofdifferentrootcanalsealers
AT pivaevandro evaluationofselectivephysicochemicalandbiologicalpropertiesofdifferentrootcanalsealers