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Development and Optimization of Imiquimod-Loaded Nanostructured Lipid Carriers Using a Hybrid Design of Experiments Approach

BACKGROUND: Imiquimod (IMQ) is an immunomodulating drug that is approved for the treatment of superficial basal cell carcinoma, actinic keratosis, external genital warts and perianal warts. However, IMQ cream (Aldara(®)) has several drawbacks including poor skin permeation, local toxicity, and compr...

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Detalles Bibliográficos
Autores principales:	Kim, Sangseo, Abdella, Sadikalmahdi, Abid, Fatima, Afinjuomo, Franklin, Youssef, Souha H, Holmes, Amy, Song, Yunmei, Vaidya, Sachin, Garg, Sanjay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968428/ https://www.ncbi.nlm.nih.gov/pubmed/36855538 http://dx.doi.org/10.2147/IJN.S400610

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