A trial of topiramate for patients with hereditary spinocerebellar ataxia

In an open pilot trial, six patients with various hereditary forms of spinocerebellar ataxia (SCA) were assigned to topiramate (50 mg/day) for 24 weeks. Four patients completed the protocol without adverse events. Of these four patients, topiramate was effective for three patients. Some patients wit...

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Detalles Bibliográficos
Autores principales: Miura, Shiroh, Sawada, Ryusuke, Yorita, Akiko, Kida, Hiroshi, Kamada, Takashi, Yamanishi, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968455/
https://www.ncbi.nlm.nih.gov/pubmed/36855409
http://dx.doi.org/10.1002/ccr3.6980
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author Miura, Shiroh
Sawada, Ryusuke
Yorita, Akiko
Kida, Hiroshi
Kamada, Takashi
Yamanishi, Yoshihiro
author_facet Miura, Shiroh
Sawada, Ryusuke
Yorita, Akiko
Kida, Hiroshi
Kamada, Takashi
Yamanishi, Yoshihiro
author_sort Miura, Shiroh
collection PubMed
description In an open pilot trial, six patients with various hereditary forms of spinocerebellar ataxia (SCA) were assigned to topiramate (50 mg/day) for 24 weeks. Four patients completed the protocol without adverse events. Of these four patients, topiramate was effective for three patients. Some patients with SCA could respond to treatment with topiramate.
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spelling pubmed-99684552023-02-27 A trial of topiramate for patients with hereditary spinocerebellar ataxia Miura, Shiroh Sawada, Ryusuke Yorita, Akiko Kida, Hiroshi Kamada, Takashi Yamanishi, Yoshihiro Clin Case Rep Case Report In an open pilot trial, six patients with various hereditary forms of spinocerebellar ataxia (SCA) were assigned to topiramate (50 mg/day) for 24 weeks. Four patients completed the protocol without adverse events. Of these four patients, topiramate was effective for three patients. Some patients with SCA could respond to treatment with topiramate. John Wiley and Sons Inc. 2023-02-26 /pmc/articles/PMC9968455/ /pubmed/36855409 http://dx.doi.org/10.1002/ccr3.6980 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Miura, Shiroh
Sawada, Ryusuke
Yorita, Akiko
Kida, Hiroshi
Kamada, Takashi
Yamanishi, Yoshihiro
A trial of topiramate for patients with hereditary spinocerebellar ataxia
title A trial of topiramate for patients with hereditary spinocerebellar ataxia
title_full A trial of topiramate for patients with hereditary spinocerebellar ataxia
title_fullStr A trial of topiramate for patients with hereditary spinocerebellar ataxia
title_full_unstemmed A trial of topiramate for patients with hereditary spinocerebellar ataxia
title_short A trial of topiramate for patients with hereditary spinocerebellar ataxia
title_sort trial of topiramate for patients with hereditary spinocerebellar ataxia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968455/
https://www.ncbi.nlm.nih.gov/pubmed/36855409
http://dx.doi.org/10.1002/ccr3.6980
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