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SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group

SARS coronavirus (SARS-CoV-2) since the year 2020 has been affecting people of all age groups involving all systems possible. The effect of COVID-19 on hematological system has been commonly seen in the form of cytopenia, prothrombotic states, or disorders of coagulation, but it has been rarely impl...

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Detalles Bibliográficos
Autores principales: Daryani, Hitesh, Jamal, Ahmed, Bhat, Vivek, Mukund, Bal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968498/
https://www.ncbi.nlm.nih.gov/pubmed/37360886
http://dx.doi.org/10.1016/j.mjafi.2022.12.016
Descripción
Sumario:SARS coronavirus (SARS-CoV-2) since the year 2020 has been affecting people of all age groups involving all systems possible. The effect of COVID-19 on hematological system has been commonly seen in the form of cytopenia, prothrombotic states, or disorders of coagulation, but it has been rarely implicated as a causal factor for hemolytic anemia in children. We present a 12-year-old male child who presented in congestive cardiac failure due to severe hemolytic anemia caused by SARS-CoV-2, with hemoglobin falling to a nadir of 1.8 g/dL. Child was diagnosed as a case of autoimmune hemolytic anemia and managed with supportive management and long-term steroids. This case highlights one of the lesser known effects of the virus, causing severe hemolysis and the role of steroids in its treatment.