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SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group

SARS coronavirus (SARS-CoV-2) since the year 2020 has been affecting people of all age groups involving all systems possible. The effect of COVID-19 on hematological system has been commonly seen in the form of cytopenia, prothrombotic states, or disorders of coagulation, but it has been rarely impl...

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Autores principales: Daryani, Hitesh, Jamal, Ahmed, Bhat, Vivek, Mukund, Bal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968498/
https://www.ncbi.nlm.nih.gov/pubmed/37360886
http://dx.doi.org/10.1016/j.mjafi.2022.12.016
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author Daryani, Hitesh
Jamal, Ahmed
Bhat, Vivek
Mukund, Bal
author_facet Daryani, Hitesh
Jamal, Ahmed
Bhat, Vivek
Mukund, Bal
author_sort Daryani, Hitesh
collection PubMed
description SARS coronavirus (SARS-CoV-2) since the year 2020 has been affecting people of all age groups involving all systems possible. The effect of COVID-19 on hematological system has been commonly seen in the form of cytopenia, prothrombotic states, or disorders of coagulation, but it has been rarely implicated as a causal factor for hemolytic anemia in children. We present a 12-year-old male child who presented in congestive cardiac failure due to severe hemolytic anemia caused by SARS-CoV-2, with hemoglobin falling to a nadir of 1.8 g/dL. Child was diagnosed as a case of autoimmune hemolytic anemia and managed with supportive management and long-term steroids. This case highlights one of the lesser known effects of the virus, causing severe hemolysis and the role of steroids in its treatment.
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spelling pubmed-99684982023-02-27 SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group Daryani, Hitesh Jamal, Ahmed Bhat, Vivek Mukund, Bal Med J Armed Forces India Case Report SARS coronavirus (SARS-CoV-2) since the year 2020 has been affecting people of all age groups involving all systems possible. The effect of COVID-19 on hematological system has been commonly seen in the form of cytopenia, prothrombotic states, or disorders of coagulation, but it has been rarely implicated as a causal factor for hemolytic anemia in children. We present a 12-year-old male child who presented in congestive cardiac failure due to severe hemolytic anemia caused by SARS-CoV-2, with hemoglobin falling to a nadir of 1.8 g/dL. Child was diagnosed as a case of autoimmune hemolytic anemia and managed with supportive management and long-term steroids. This case highlights one of the lesser known effects of the virus, causing severe hemolysis and the role of steroids in its treatment. Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd. 2023-02-26 /pmc/articles/PMC9968498/ /pubmed/37360886 http://dx.doi.org/10.1016/j.mjafi.2022.12.016 Text en © 2023 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Daryani, Hitesh
Jamal, Ahmed
Bhat, Vivek
Mukund, Bal
SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group
title SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group
title_full SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group
title_fullStr SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group
title_full_unstemmed SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group
title_short SARS-CoV-2-induced autoimmune hemolytic anemia in pediatric age-group
title_sort sars-cov-2-induced autoimmune hemolytic anemia in pediatric age-group
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968498/
https://www.ncbi.nlm.nih.gov/pubmed/37360886
http://dx.doi.org/10.1016/j.mjafi.2022.12.016
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