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Arbaclofen extended-release tablets for spasticity in multiple sclerosis: open-label extension study
Baclofen, a racemic γ-aminobutyric acid B receptor agonist, is commonly used for the management of multiple sclerosis–related spasticity but is associated with frequent dosing and poor tolerability. Arbaclofen, the active R-enantiomer of baclofen, exhibits 100- to 1000-fold greater specificity for t...
Autores principales: | Okuda, Darin T, Kantor, Daniel, Jaros, Mark, deVries, Tina, Hunter, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968651/ https://www.ncbi.nlm.nih.gov/pubmed/36861013 http://dx.doi.org/10.1093/braincomms/fcad026 |
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