Cargando…
A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe
Current approaches for the assessment of environmental and human health risks due to exposure to chemical substances have served their purpose reasonably well. Nevertheless, the systems in place for different uses of chemicals are faced with various challenges, ranging from a growing number of chemi...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968685/ https://www.ncbi.nlm.nih.gov/pubmed/36645448 http://dx.doi.org/10.1007/s00204-022-03435-7 |
_version_ | 1784897552672358400 |
---|---|
author | Marx-Stoelting, P. Rivière, G. Luijten, M. Aiello-Holden, K. Bandow, N. Baken, K. Cañas, A. Castano, A. Denys, S. Fillol, C. Herzler, M. Iavicoli, I. Karakitsios, S. Klanova, J. Kolossa-Gehring, M. Koutsodimou, A. Vicente, J. Lobo Lynch, I. Namorado, S. Norager, S. Pittman, A. Rotter, S. Sarigiannis, D. Silva, M. J. Theunis, J. Tralau, T. Uhl, M. van Klaveren, J. Wendt-Rasch, L. Westerholm, E. Rousselle, C. Sanders, P. |
author_facet | Marx-Stoelting, P. Rivière, G. Luijten, M. Aiello-Holden, K. Bandow, N. Baken, K. Cañas, A. Castano, A. Denys, S. Fillol, C. Herzler, M. Iavicoli, I. Karakitsios, S. Klanova, J. Kolossa-Gehring, M. Koutsodimou, A. Vicente, J. Lobo Lynch, I. Namorado, S. Norager, S. Pittman, A. Rotter, S. Sarigiannis, D. Silva, M. J. Theunis, J. Tralau, T. Uhl, M. van Klaveren, J. Wendt-Rasch, L. Westerholm, E. Rousselle, C. Sanders, P. |
author_sort | Marx-Stoelting, P. |
collection | PubMed |
description | Current approaches for the assessment of environmental and human health risks due to exposure to chemical substances have served their purpose reasonably well. Nevertheless, the systems in place for different uses of chemicals are faced with various challenges, ranging from a growing number of chemicals to changes in the types of chemicals and materials produced. This has triggered global awareness of the need for a paradigm shift, which in turn has led to the publication of new concepts for chemical risk assessment and explorations of how to translate these concepts into pragmatic approaches. As a result, next-generation risk assessment (NGRA) is generally seen as the way forward. However, incorporating new scientific insights and innovative approaches into hazard and exposure assessments in such a way that regulatory needs are adequately met has appeared to be challenging. The European Partnership for the Assessment of Risks from Chemicals (PARC) has been designed to address various challenges associated with innovating chemical risk assessment. Its overall goal is to consolidate and strengthen the European research and innovation capacity for chemical risk assessment to protect human health and the environment. With around 200 participating organisations from all over Europe, including three European agencies, and a total budget of over 400 million euro, PARC is one of the largest projects of its kind. It has a duration of seven years and is coordinated by ANSES, the French Agency for Food, Environmental and Occupational Health & Safety. |
format | Online Article Text |
id | pubmed-9968685 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-99686852023-02-28 A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe Marx-Stoelting, P. Rivière, G. Luijten, M. Aiello-Holden, K. Bandow, N. Baken, K. Cañas, A. Castano, A. Denys, S. Fillol, C. Herzler, M. Iavicoli, I. Karakitsios, S. Klanova, J. Kolossa-Gehring, M. Koutsodimou, A. Vicente, J. Lobo Lynch, I. Namorado, S. Norager, S. Pittman, A. Rotter, S. Sarigiannis, D. Silva, M. J. Theunis, J. Tralau, T. Uhl, M. van Klaveren, J. Wendt-Rasch, L. Westerholm, E. Rousselle, C. Sanders, P. Arch Toxicol Letter to the Editor, News and Views Current approaches for the assessment of environmental and human health risks due to exposure to chemical substances have served their purpose reasonably well. Nevertheless, the systems in place for different uses of chemicals are faced with various challenges, ranging from a growing number of chemicals to changes in the types of chemicals and materials produced. This has triggered global awareness of the need for a paradigm shift, which in turn has led to the publication of new concepts for chemical risk assessment and explorations of how to translate these concepts into pragmatic approaches. As a result, next-generation risk assessment (NGRA) is generally seen as the way forward. However, incorporating new scientific insights and innovative approaches into hazard and exposure assessments in such a way that regulatory needs are adequately met has appeared to be challenging. The European Partnership for the Assessment of Risks from Chemicals (PARC) has been designed to address various challenges associated with innovating chemical risk assessment. Its overall goal is to consolidate and strengthen the European research and innovation capacity for chemical risk assessment to protect human health and the environment. With around 200 participating organisations from all over Europe, including three European agencies, and a total budget of over 400 million euro, PARC is one of the largest projects of its kind. It has a duration of seven years and is coordinated by ANSES, the French Agency for Food, Environmental and Occupational Health & Safety. Springer Berlin Heidelberg 2023-01-16 2023 /pmc/articles/PMC9968685/ /pubmed/36645448 http://dx.doi.org/10.1007/s00204-022-03435-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Letter to the Editor, News and Views Marx-Stoelting, P. Rivière, G. Luijten, M. Aiello-Holden, K. Bandow, N. Baken, K. Cañas, A. Castano, A. Denys, S. Fillol, C. Herzler, M. Iavicoli, I. Karakitsios, S. Klanova, J. Kolossa-Gehring, M. Koutsodimou, A. Vicente, J. Lobo Lynch, I. Namorado, S. Norager, S. Pittman, A. Rotter, S. Sarigiannis, D. Silva, M. J. Theunis, J. Tralau, T. Uhl, M. van Klaveren, J. Wendt-Rasch, L. Westerholm, E. Rousselle, C. Sanders, P. A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe |
title | A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe |
title_full | A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe |
title_fullStr | A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe |
title_full_unstemmed | A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe |
title_short | A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe |
title_sort | walk in the parc: developing and implementing 21st century chemical risk assessment in europe |
topic | Letter to the Editor, News and Views |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968685/ https://www.ncbi.nlm.nih.gov/pubmed/36645448 http://dx.doi.org/10.1007/s00204-022-03435-7 |
work_keys_str_mv | AT marxstoeltingp awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT riviereg awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT luijtenm awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT aielloholdenk awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT bandown awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT bakenk awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT canasa awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT castanoa awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT denyss awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT fillolc awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT herzlerm awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT iavicolii awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT karakitsioss awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT klanovaj awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT kolossagehringm awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT koutsodimoua awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT vicentejlobo awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT lynchi awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT namorados awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT noragers awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT pittmana awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT rotters awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT sarigiannisd awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT silvamj awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT theunisj awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT tralaut awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT uhlm awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT vanklaverenj awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT wendtraschl awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT westerholme awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT roussellec awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT sandersp awalkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT marxstoeltingp walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT riviereg walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT luijtenm walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT aielloholdenk walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT bandown walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT bakenk walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT canasa walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT castanoa walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT denyss walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT fillolc walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT herzlerm walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT iavicolii walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT karakitsioss walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT klanovaj walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT kolossagehringm walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT koutsodimoua walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT vicentejlobo walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT lynchi walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT namorados walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT noragers walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT pittmana walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT rotters walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT sarigiannisd walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT silvamj walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT theunisj walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT tralaut walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT uhlm walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT vanklaverenj walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT wendtraschl walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT westerholme walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT roussellec walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope AT sandersp walkintheparcdevelopingandimplementing21stcenturychemicalriskassessmentineurope |