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Epstein-Barr virus DNA seropositivity links distinct tumoral heterogeneity and immune landscape in nasopharyngeal carcinoma

BACKGROUND: Epstein-Barr virus (EBV) DNA seronegative (Sero-) and seropositive (Sero+) nasopharyngeal carcinoma (NPC) are distinctly different disease subtypes. Patients with higher baseline EBV DNA titers seem to benefit less from anti-PD1 immunotherapy, but underlying mechanisms remain unclear. Tu...

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Detalles Bibliográficos
Autores principales: Li, Wangzhong, Lv, Shuhui, Liu, Guoying, Lu, Nian, Jiang, Yaofei, Liang, Hu, Xia, Weixiong, Xiang, Yanqun, Xie, Changqing, He, Jianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968721/
https://www.ncbi.nlm.nih.gov/pubmed/36860875
http://dx.doi.org/10.3389/fimmu.2023.1124066